Products 522-17-8
CAS 522-17-8 appears in our catalog under these names: Deguelin, 95%, Deguelin, >95% (HPLC), Deguelin/ 98.26% (existing batch purity), Deguelin, (-)-Deguelin, >95.0%(HPLC). Offered by: Combi-blocks, TRC, TargetMol, GLPBio, Biosynth. Available pack sizes: 100mg, 10mg, 50mg, 5mg, 25mg, 250mg, 1mg, 1g.
Deguelin is a rotenone that is 13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one substituted by methoxy groups at positions 9 and 10, and by two methyl groups at position 3 (the 7aS,13aS-stereoisomer). It exists in abundant quantities in the bark, roots, and leaves of the Leguminosae family of plants and reported to exert anti-tumour effects in various cancers. It has a role as an antiviral agent, an antineoplastic agent, a mitochondrial NADH:ubiquinone reductase inhibitor, an angiogenesis inhibitor, an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor, an anti-inflammatory agent, an apoptosis inducer and a plant metabolite. It is an aromatic ether, an organic heteropentacyclic compound, a diether and a member of rotenones.
Source: ChEBI
| Molecular formula | C23H22O6 |
|---|---|
| Molecular weight | 394.4 g/mol |
| IUPAC name | (1S,14S)-17,18-dimethoxy-7,7-dimethyl-2,8,21-trioxapentacyclo[12.8.0.03,12.04,9.015,20]docosa-3(12),4(9),5,10,15,17,19-heptaen-13-one |
| InChIKey | ORDAZKGHSNRHTD-UXHICEINSA-N |
| SMILES | CC1(C=CC2=C(O1)C=CC3=C2O[C@@H]4COC5=CC(=C(C=C5[C@@H]4C3=O)OC)OC)C |
Computed by PubChem (NCBI)