Demecolcine
cas: 477-30-5 — see every product listed under this CAS number, including other names
Demecolcine (CAS 477-30-5) is a chemical reagent available from Chemat. Available pack sizes: on request, 25mg, 10mg, 50MG, 5MG. Offered by: Chemat Brand, Biosynth, Sigma-Aldrich.
| brand | Chemat Brand |
|---|---|
| catalog number | ULC1533 |
| cas | 477-30-5 |
| size | on request |
| availability | Do potwierdzenia przez Chemat|To be confirmed by Chemat |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat Brand | on request | price on request | |
| Biosynth | 25mg | price on request | |
| Biosynth | 10mg | price on request | |
| Sigma-Aldrich | 10MG | 2350.00 Pln | |
| Sigma-Aldrich | 50MG | 7740.00 Pln | |
| Sigma-Aldrich | 5MG | 1460.00 Pln |
properties
| purity | No data |
|---|---|
| category | Chemicals |
| delivery time | To be confirmed by Chemat |
(-)-demecolcine is a secondary amino compound that is (S)-colchicine in which the N-acetyl group is replaced by an N-methyl group. Isolable from the autumn crocus, Colchicum autumnale, it is less toxic than colchicine and is used as an antineoplastic. It has a role as an antineoplastic agent and a microtubule-destabilising agent. It is an alkaloid and a secondary amino compound.
Source: ChEBI
| Molecular formula | C21H25NO5 |
|---|---|
| Molecular weight | 371.4 g/mol |
| IUPAC name | (7S)-1,2,3,10-tetramethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one |
| InChIKey | NNJPGOLRFBJNIW-HNNXBMFYSA-N |
| SMILES | CN[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC |
Computed by PubChem (NCBI)
Synonyms:
Demecolcine, colcemid, Demecolcin, Desmecolcine, Kolchamin, Kolkamin, Omaine, Omain, Santavy's substance F, Methylcolchicine