Fasudil
cas: 103745-39-7 — see every product listed under this CAS number, including other names
Fasudil (CAS 103745-39-7) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 200mg, 500mg, 0,5g, 50mg. Offered by: TRC, GLPBio, Biosynth.
| brand | TRC |
|---|---|
| catalog number | TRC-F150023-100MG |
| cas | 103745-39-7 |
| size | 100mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| TRC | 100mg | price on request | |
| GLPBio | 200mg | 634.48 Pln | |
| GLPBio | 500mg | 831.06 Pln | |
| Biosynth | 0,5g | price on request | |
| Biosynth | 50mg | price on request |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Fasudil is an isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia. It has a role as a geroprotector, a vasodilator agent, an antihypertensive agent, a calcium channel blocker, an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor, a neuroprotective agent and a nootropic agent. It is a member of isoquinolines and a N-sulfonyldiazepane. It is a conjugate base of a fasudil(1+).
Source: ChEBI
| Molecular formula | C14H17N3O2S |
|---|---|
| Molecular weight | 291.37 g/mol |
| IUPAC name | 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline |
| InChIKey | NGOGFTYYXHNFQH-UHFFFAOYSA-N |
| SMILES | C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3 |
Computed by PubChem (NCBI)
Synonyms:
Fasudil, ha-1077, Fasudilum, 1H-1,4-Diazepine, hexahydro-1-(5-isoquinolinylsulfonyl)-, 1-(5-Isoquinolinesulfonyl)homopiperazine, Hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine, 5-[(Hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]isoquinoline, 5-(1,4-diazepane-1-sulfonyl)isoquinoline, 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline, Fasudil [INN]