Flavopiridol 98%

cas: 146426-40-6 — see every product listed under this CAS number, including other names

Flavopiridol 98% (CAS 146426-40-6) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 250mg, 1g. Offered by: Ambeed.

brandAmbeed
catalog numberA172904-1mg
cas146426-40-6
size1mg
Documents: Safety Data Sheet (MSDS)
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Available pack sizes

brand size price
Ambeed 1mg 220.19 Pln
Ambeed 5mg 320.31 Pln
Ambeed 10mg 420.44 Pln
Ambeed 25mg 765.31 Pln
Ambeed 50mg 1060.12 Pln
Ambeed 100mg 1549.62 Pln
Ambeed 250mg 3541.00 Pln
Ambeed 1g 8758.62 Pln

properties

purity98%
delivery time 1-2 weeks
ambeed catalog no.A172904
Structural formula: {0} (CAS {1})

Alvocidib is a synthetic dihydroxyflavone that is 5,7-dihydroxyflavone which is substituted by a 3-hydroxy-1-methylpiperidin-4-yl group at position 8 and by a chlorine at the 2' position (the ()-3S,4R stereoisomer). A cyclin-dependent kinase 9 (CDK9) inhibitor, it has been studied for the treatment of acute myeloid leukaemia, arthritis and atherosclerotic plaque formation. It has a role as an antineoplastic agent, an antirheumatic drug, an apoptosis inducer and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is a dihydroxyflavone, a hydroxypiperidine, a tertiary amino compound and a member of monochlorobenzenes. It is a conjugate base of an alvocidib(1+).

Source: ChEBI

Identity
Molecular formulaC21H20ClNO5
Molecular weight401.8 g/mol
IUPAC name2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]chromen-4-one
InChIKeyBIIVYFLTOXDAOV-YVEFUNNKSA-N
SMILESCN1CC[C@@H]([C@@H](C1)O)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O

Computed by PubChem (NCBI)

Synonyms: Flavopiridol, Alvocidib, Alvocidib freebase, alvocidibum, Flavopiridol (Alvocidib), ALVOCIDIB [MART.], Alvocidib [INN], Flavoperidol, Alvocidib [USAN], Alvocidib [USAN:INN]
Isomers (same molecular formula)
(Z)-but-2-enedioic acid;(2S,6S)-9-chloro-4-methyl-13-oxa-4-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaene C21H20ClNO5
2-(2-chlorophenyl)-5,7-dihydroxy-8-[(2S,3R)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl]chromen-4-one C21H20ClNO5
(Z)-but-2-enedioic acid;(2R,6R)-9-chloro-4-methyl-13-oxa-4-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaene C21H20ClNO5
(E)-but-2-enedioic acid;(2S,6S)-9-chloro-4-methyl-13-oxa-4-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaene C21H20ClNO5
(Z)-but-2-enedioic acid;(2S,6R)-9-chloro-4-methyl-13-oxa-4-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaene C21H20ClNO5

Also listed as

Alvocidib (Flavopiridol) Chemat Brand CAS 146426-40-6
Flavopiridol/ 99.85% (existing batch purity) TargetMol CAS 146426-40-6
Flavopiridol GLPBio CAS 146426-40-6
2-(2-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one, 98%, 98% Chemat CAS 146426-40-6
Flavopiridol, 99.72% MedChemExpress CAS 146426-40-6
Flavopiridol (Standard) MedChemExpress CAS 146426-40-6