Formestane, min. 95 %, 5 g
cas: 566-48-3 — see every product listed under this CAS number, including other names
Formestane, min. 95 %, 5 g (CAS 566-48-3) is a chemical reagent available from Chemat. Available pack sizes: 5g. Offered by: Roth.
| brand | Roth |
|---|---|
| catalog number | ROTH-2LPY.3 |
| cas | 566-48-3 |
| size | 5g |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Roth | 5g | 1835.93 Pln |
properties
| delivery time | 2 week |
|---|
Formestane is a 17-oxo steroid that is androst-4-ene-3,17-dione in which the hydrogen at position 4 is replaced by a hydroxy group. Formestane was the first selective, type I steroidal aromatase inhibitor, suppressing oestrogen production from anabolic steroids or prohormones. It was formerly used in the treatment of oestrogen-receptor positive breast cancer in post-meopausal women. As it has poor oral bioavailability, it had to be administered by (fortnightly) intramuscular injection. It fell out of use with the subsequent development of cheaper, orally active aromatase inhibitors. Formestane is listed by the World Anti-Doping Agency as a substance prohibited from use by athletes. It has a role as an antineoplastic agent and an EC 1.14.14.14 (aromatase) inhibitor. It is a 17-oxo steroid, an enol, a hydroxy steroid and a 3-oxo-Delta(4) steroid. It derives from a hydride of an androstane.
Source: ChEBI
| Molecular formula | C19H26O3 |
|---|---|
| Molecular weight | 302.4 g/mol |
| IUPAC name | (8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione |
| InChIKey | OSVMTWJCGUFAOD-KZQROQTASA-N |
| SMILES | C[C@]12CCC(=O)C(=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)O |
Computed by PubChem (NCBI)