Gemcitabine base
cas: 95058-81-4 — see every product listed under this CAS number, including other names
Gemcitabine base (CAS 95058-81-4) is a chemical reagent available from Chemat. Available pack sizes: 25g, 10g, 50g, 250g, 100g. Offered by: Biosynth.
| brand | Biosynth |
|---|---|
| catalog number | ND04237-25g |
| cas | 95058-81-4 |
| size | 25g |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Biosynth | 25g | price on request | |
| Biosynth | 10g | price on request | |
| Biosynth | 50g | price on request | |
| Biosynth | 250g | price on request | |
| Biosynth | 100g | price on request |
properties
| category | Nucleosides |
|---|---|
| sub-category 1 | Nucleosides, Nucleotides and Nucleic acids |
| purity | No data |
| delivery time | 1-2 weeks |
Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer. It has a role as a radiosensitizing agent, an antimetabolite, an antineoplastic agent, a xenobiotic, an immunosuppressive agent, an antiviral drug, a photosensitizing agent, a prodrug, a DNA synthesis inhibitor, an EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor and an environmental contaminant. It is a pyrimidine 2'-deoxyribonucleoside and an organofluorine compound.
Source: ChEBI
| Molecular formula | C9H11F2N3O4 |
|---|---|
| Molecular weight | 263.20 g/mol |
| IUPAC name | 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one |
| InChIKey | SDUQYLNIPVEERB-QPPQHZFASA-N |
| SMILES | C1=CN(C(=O)N=C1N)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F |
Computed by PubChem (NCBI)