Products 95058-81-4
CAS 95058-81-4 appears in our catalog under these names: Gemcitabine base, min. 95 %, 25 g, Gemcitabine, Gemcitabine, >95% (HPLC), Gemcitabine/ 99.67% (existing batch purity), Gemcitabine, 98.00%. Offered by: Roth, Chemat Brand, TRC, TargetMol, GLPBio. Available pack sizes: 25g, on request, 100mg, 1g, 250mg, 50mg, 200mg, 500mg.
Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer. It has a role as a radiosensitizing agent, an antimetabolite, an antineoplastic agent, a xenobiotic, an immunosuppressive agent, an antiviral drug, a photosensitizing agent, a prodrug, a DNA synthesis inhibitor, an EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor and an environmental contaminant. It is a pyrimidine 2'-deoxyribonucleoside and an organofluorine compound.
Source: ChEBI
| Molecular formula | C9H11F2N3O4 |
|---|---|
| Molecular weight | 263.20 g/mol |
| IUPAC name | 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one |
| InChIKey | SDUQYLNIPVEERB-QPPQHZFASA-N |
| SMILES | C1=CN(C(=O)N=C1N)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F |
Computed by PubChem (NCBI)