Gemcitabine

cas: 95058-81-4 — see every product listed under this CAS number, including other names

Gemcitabine (CAS 95058-81-4) is a chemical reagent available from Chemat. Available pack sizes: on request, 100mg, 10mM (in 1ml dmso). Offered by: Chemat Brand, GLPBio.

brandChemat Brand
catalog numberULG261
cas95058-81-4
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
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Available pack sizes

brand size price
Chemat Brand on request price on request
GLPBio 100mg 578.32 Pln
GLPBio 10mM (in 1ml dmso) 587.68 Pln

properties

purityNo data
categoryChemicals
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer. It has a role as a radiosensitizing agent, an antimetabolite, an antineoplastic agent, a xenobiotic, an immunosuppressive agent, an antiviral drug, a photosensitizing agent, a prodrug, a DNA synthesis inhibitor, an EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor and an environmental contaminant. It is a pyrimidine 2'-deoxyribonucleoside and an organofluorine compound.

Source: ChEBI

Identity
Molecular formulaC9H11F2N3O4
Molecular weight263.20 g/mol
IUPAC name4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
InChIKeySDUQYLNIPVEERB-QPPQHZFASA-N
SMILESC1=CN(C(=O)N=C1N)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F

Computed by PubChem (NCBI)

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