Idasanutlin 98%

cas: 1229705-06-9 — see every product listed under this CAS number, including other names

Idasanutlin 98% (CAS 1229705-06-9) is a chemical reagent available from Chemat. Available pack sizes: 5g, 1mg, 2mg, 5mg, 10mg, 50mg, 100mg, 250mg. Offered by: Ambeed.

brandAmbeed
catalog numberA124368-5g
cas1229705-06-9
size5g
Documents: Safety Data Sheet (MSDS)
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Available pack sizes

brand size price
Ambeed 5g 12535.56 Pln
Ambeed 1mg 175.69 Pln
Ambeed 2mg 203.50 Pln
Ambeed 5mg 248.00 Pln
Ambeed 10mg 303.62 Pln
Ambeed 50mg 715.25 Pln
Ambeed 100mg 843.19 Pln
Ambeed 250mg 1482.88 Pln
Ambeed 1g 3630.00 Pln

properties

purity98%
delivery time 1-2 weeks
ambeed catalog no.A124368
Structural formula: {0} (CAS {1})

Idasanutlin is an orally available, small molecule, antagonist of MDM2 (mouse double minute 2; Mdm2 p53 binding protein homolog), with potential antineoplastic activity. Idasanutlin binds to MDM2 blocking the interaction between the MDM2 protein and the transcriptional activation domain of the tumor suppressor protein p53. By preventing the MDM2-p53 interaction, p53 is not enzymatically degraded and the transcriptional activity of p53 is restored. This may lead to p53-mediated induction of tumor cell apoptosis. MDM2, a zinc finger nuclear phosphoprotein and negative regulator of the p53 pathway, is often overexpressed in cancer cells and has been implicated in cancer cell proliferation and survival.

Source: ChEBI

Identity
Molecular formulaC31H29Cl2F2N3O4
Molecular weight616.5 g/mol
IUPAC name4-[[(2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carbonyl]amino]-3-methoxybenzoic acid
InChIKeyTVTXCJFHQKSQQM-LJQIRTBHSA-N
SMILESCC(C)(C)C[C@H]1[C@]([C@H]([C@@H](N1)C(=O)NC2=C(C=C(C=C2)C(=O)O)OC)C3=C(C(=CC=C3)Cl)F)(C#N)C4=C(C=C(C=C4)Cl)F

Computed by PubChem (NCBI)

Synonyms: Idasanutlin, Idasanutlina, Idasanutline, idasanutlinum, Idasanutlin (RG-7388), Idasanutlin (RG7388), C31H29Cl2F2N3O4, Idasanutlin [USAN:INN], IDASANUTLIN [INN], Idasanutlin (USAN/INN)

Also listed as

Idasanutlin TRC CAS 1229705-06-9
RG7388 GLPBio CAS 1229705-06-9
Idasanutlin/ 99.86% (existing batch purity) TargetMol CAS 1229705-06-9
RG 7388 Biosynth CAS 1229705-06-9
Idasanutlin, 99.93% MedChemExpress CAS 1229705-06-9
Idasanutlin (Standard) MedChemExpress CAS 1229705-06-9
4-[[[(2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-2-pyrrolidinyl]carbonyl]amino]-3-methoxybenzoic acid, 98%, 98% Chemat CAS 1229705-06-9
Idasanutlin, 98% Fluorochem CAS 1229705-06-9