MK–2461

cas: 917879-39-1 — see every product listed under this CAS number, including other names

MK–2461 (CAS 917879-39-1) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 5mg, 10mM (in 1ml dmso). Offered by: GLPBio.

brandGLPBio
catalog numberGC16337-10
cas917879-39-1
size10mg
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Available pack sizes

brand size price
GLPBio 10mg 1462.93 Pln
GLPBio 5mg 1055.73 Pln
GLPBio 10mM (in 1ml dmso) 1065.09 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

MK-2461 is a member of the class of benzocycloheptapyridines that is 5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one substituted by 1-methyl-1H-pyrazol-4-yl and [{[(2R)-1,4-dioxan-2-yl]methyl}(methyl)sulfamoyl]amino groups at positions 3 and 7, respectively. It is a novel ATP-competitive multi-targeted inhibitor of activated c-Met (IC50 = 2.5 nM). It has a role as an antineoplastic agent, an apoptosis inducer and a c-Met tyrosine kinase inhibitor. It is a member of pyrazoles, a member of dioxanes, a benzocycloheptapyridine and a member of sulfamides.

Source: ChEBI

Identity
Molecular formulaC24H25N5O5S
Molecular weight495.6 g/mol
IUPAC name14-[[[(2R)-1,4-dioxan-2-yl]methyl-methylsulfamoyl]amino]-5-(1-methylpyrazol-4-yl)-2-oxo-7-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaene
InChIKeyJGEBLDKNWBUGRZ-HXUWFJFHSA-N
SMILESCN1C=C(C=N1)C2=CC3=C(C=CC4=C(C3=O)C=C(C=C4)NS(=O)(=O)N(C)C[C@@H]5COCCO5)N=C2

Computed by PubChem (NCBI)

Synonyms: JGEBLDKNWBUGRZ-HXUWFJFHSA-N, orb1223655, orb1689093

Also listed as

MK-2461 TRC CAS 917879-39-1
MK-2461/ 99.53% (existing batch purity) TargetMol CAS 917879-39-1
N-[(2R)-1,4-Dioxan-2-ylmethyl]-N-methyl-N'-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]sulfamide, 98%, 98% Chemat CAS 917879-39-1
MK-2461, 99.28% MedChemExpress CAS 917879-39-1