MK-2461

cas: 917879-39-1 — see every product listed under this CAS number, including other names

MK-2461 (CAS 917879-39-1) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 10mg, 25mg, 1mg, 5mg, 50mg. Offered by: TRC, Biosynth, Chemat.

brandTRC
catalog numberTRC-M425035-100MG
cas917879-39-1
size100mg
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Available pack sizes

brand size price
TRC 100mg price on request
Biosynth 10mg price on request
Biosynth 25mg price on request
Chemat 10mg 4672.02 Pln
Chemat 1mg 1913.64 Pln
Chemat 5mg 2941.27 Pln
Biosynth 50mg price on request
Biosynth 100mg price on request

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

MK-2461 is a member of the class of benzocycloheptapyridines that is 5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one substituted by 1-methyl-1H-pyrazol-4-yl and [{[(2R)-1,4-dioxan-2-yl]methyl}(methyl)sulfamoyl]amino groups at positions 3 and 7, respectively. It is a novel ATP-competitive multi-targeted inhibitor of activated c-Met (IC50 = 2.5 nM). It has a role as an antineoplastic agent, an apoptosis inducer and a c-Met tyrosine kinase inhibitor. It is a member of pyrazoles, a member of dioxanes, a benzocycloheptapyridine and a member of sulfamides.

Source: ChEBI

Identity
Molecular formulaC24H25N5O5S
Molecular weight495.6 g/mol
IUPAC name14-[[[(2R)-1,4-dioxan-2-yl]methyl-methylsulfamoyl]amino]-5-(1-methylpyrazol-4-yl)-2-oxo-7-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaene
InChIKeyJGEBLDKNWBUGRZ-HXUWFJFHSA-N
SMILESCN1C=C(C=N1)C2=CC3=C(C=CC4=C(C3=O)C=C(C=C4)NS(=O)(=O)N(C)C[C@@H]5COCCO5)N=C2

Computed by PubChem (NCBI)

Synonyms: JGEBLDKNWBUGRZ-HXUWFJFHSA-N, orb1223655, orb1689093

Also listed as

MK-2461/ 99.53% (existing batch purity) TargetMol CAS 917879-39-1
MK–2461 GLPBio CAS 917879-39-1
N-[(2R)-1,4-Dioxan-2-ylmethyl]-N-methyl-N'-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]sulfamide, 98%, 98% Chemat CAS 917879-39-1
MK-2461, 99.28% MedChemExpress CAS 917879-39-1