Mefuparib, 99.77%
cas: 1392502-82-7 — see every product listed under this CAS number, including other names
Mefuparib, 99.77% (CAS 1392502-82-7) is a chemical reagent available from Chemat. Available pack sizes: 100 mg, 5 mg, 25 mg, 10 mg, 50 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-167927-100 mg |
| cas | 1392502-82-7 |
| size | 100 mg |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 100 mg | 4675.76 Pln | |
| MedChemExpress | 5 mg | 677.28 Pln | |
| MedChemExpress | 25 mg | 1903.30 Pln | |
| MedChemExpress | 10 mg | 1011.65 Pln | |
| MedChemExpress | 50 mg | 2976.06 Pln |
properties
| delivery time | 2-3 weeks |
|---|---|
| purity | 99.77% |
Mefuparib is a member of the class of 1-benzofurans that is 1-benzofuran substituted by 4-[(methylamino)methyl]phenyl, fluoro and aminocarbonyl groups at positions 2, 5, and 7, respectively. It is a potent inhibitor of poly(ADP-ribose) polymerases PARP1 and PARP2 (IC50 of 3.2 nM and 1.9 nM, respectively). The compound exhibits anti-cancer properties and has also shown promising antiviral activity against the virus that causes COVID-19. It has a role as an anticoronaviral agent, an antineoplastic agent, an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor and an apoptosis inducer. It is a primary carboxamide, an organofluorine compound, a member of 1-benzofurans and a secondary amino compound. It is a conjugate base of a mefuparib(1+).
Source: ChEBI
| Molecular formula | C17H15FN2O2 |
|---|---|
| Molecular weight | 298.31 g/mol |
| IUPAC name | 5-fluoro-2-[4-(methylaminomethyl)phenyl]-1-benzofuran-7-carboxamide |
| InChIKey | ROBJKLPZIPNAMV-UHFFFAOYSA-N |
| SMILES | CNCC1=CC=C(C=C1)C2=CC3=CC(=CC(=C3O2)C(=O)N)F |
Computed by PubChem (NCBI)
Synonyms:
Mefuparib, MEFUPARIB [WHO-DD], 5-Fluoro-2-(4-((methylamino)methyl)phenyl)-7-benzofurancarboxamide, 5-fluoro-2-{4-[(methylamino)methyl]phenyl}-1-benzofuran-7-carboxamide, 5-Fluoro-2-[4-[(methylamino)methyl]phenyl]-7-benzofurancarboxamide, 5-fluoro-2-(4-((methylamino)methyl)phenyl)-1-benzofuran-7-carboxamide, Mefuparib Free Base, ROBJKLPZIPNAMV-UHFFFAOYSA-N, 5-fluoro-2-{4-[(methylamino)methyl]phenyl}-benzofuran-7-carboxamide, 5-fluoro-2-{4-[(methylamino)methyl]phenyl}benzofuran-7-carboxamide