N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamicacid, 99+%, 99+%
cas: 137281-23-3 — see every product listed under this CAS number, including other names
N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamicacid, 99+%, 99+% (CAS 137281-23-3) is a chemical reagent available from Chemat. Available pack sizes: 250mg, 1g, 5g, 1mg. Offered by: Chemat.
| brand | Chemat |
|---|---|
| catalog number | Ch11242R-250mg |
| cas | 137281-23-3 |
| size | 250mg |
| availability | 15g |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat | 250mg | 117.20 Pln | |
| Chemat | 1g | 165.20 Pln | |
| Chemat | 5g | 486.80 Pln | |
| Chemat | 1mg | 78.80 Pln |
properties
| purity | 99+% |
|---|---|
| delivery time | 3 weeks |
Pemetrexed is an N-acylglutamic acid in which the N-acyl group is specified as 4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl. Inhibits thymidylate synthase (TS), 421 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT). It has a role as an antimetabolite, an antineoplastic agent, an EC 1.5.1.3 (dihydrofolate reductase) inhibitor, an EC 2.1.1.45 (thymidylate synthase) inhibitor and an EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor. It is a N-acyl-L-glutamic acid and a pyrrolopyrimidine. It is a conjugate acid of a pemetrexed(2-).
Source: ChEBI
| Molecular formula | C20H21N5O6 |
|---|---|
| Molecular weight | 427.4 g/mol |
| IUPAC name | (2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid |
| InChIKey | WBXPDJSOTKVWSJ-ZDUSSCGKSA-N |
| SMILES | C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)O)C(=O)O |
Computed by PubChem (NCBI)