PD-166866 99%
cas: 192705-79-6 — see every product listed under this CAS number, including other names
PD-166866 99% (CAS 192705-79-6) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 250mg. Offered by: Ambeed.
| brand | Ambeed |
|---|---|
| catalog number | A339638-1mg |
| cas | 192705-79-6 |
| size | 1mg |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Ambeed | 1mg | 186.81 Pln | |
| Ambeed | 5mg | 309.19 Pln | |
| Ambeed | 10mg | 448.25 Pln | |
| Ambeed | 25mg | 548.38 Pln | |
| Ambeed | 50mg | 698.56 Pln | |
| Ambeed | 100mg | 1065.69 Pln | |
| Ambeed | 250mg | 2061.38 Pln |
properties
| purity | 99% |
|---|---|
| delivery time | 2-3 weeks |
| ambeed catalog no. | A339638 |
PD-166866 is a member of the class of pyridopyrimidines that is pyrido[2,3-d]pyrimidine substituted by an amino group at position 2, 3,5-dimethoxyphenyl group at position 6, and by a (tert-butylcarbamoyl)nitrilo group at position 7. It is a selective ATP competitive inhibitor of the human fibroblast growth factor-1 receptor (FGFR1) tyrosine kinase with an IC50 of 52.4 nM. It has a role as an antineoplastic agent, an angiogenesis inhibitor, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an apoptosis inducer. It is a pyridopyrimidine, a member of ureas, a primary arylamine, a dimethoxybenzene and a biaryl.
Source: ChEBI
| Molecular formula | C20H24N6O3 |
|---|---|
| Molecular weight | 396.4 g/mol |
| IUPAC name | 1-[2-amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea |
| InChIKey | NHJSWORVNIOXIT-UHFFFAOYSA-N |
| SMILES | CC(C)(C)NC(=O)NC1=C(C=C2C=NC(=NC2=N1)N)C3=CC(=CC(=C3)OC)OC |
Computed by PubChem (NCBI)