PF–06840003 (EOS200271)
cas: 198474-05-4 — see every product listed under this CAS number, including other names
PF–06840003 (EOS200271) (CAS 198474-05-4) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 10mg, 100mg, 10mM (in 1ml dmso), 5mg, 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC32879-1 |
| cas | 198474-05-4 |
| size | 1mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 1mg | 648.53 Pln | |
| GLPBio | 10mg | 1018.28 Pln | |
| GLPBio | 100mg | 3639.36 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 1018.28 Pln | |
| GLPBio | 5mg | 779.58 Pln | |
| GLPBio | 50mg | 2352.23 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Pf-06840003 is iDO1 Inhibitor PF-06840003 is an orally available hydroxyamidine and inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with potential immunomodulating and antineoplastic activities. Upon administration, IDO1 inhibitor PF-06840003 targets and binds to IDO1, an enzyme responsible for the oxidation of tryptophan into kynurenine.
Source: ChEBI
| Molecular formula | C12H9FN2O2 |
|---|---|
| Molecular weight | 232.21 g/mol |
| IUPAC name | 3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione |
| InChIKey | MXKLDYKORJEOPR-UHFFFAOYSA-N |
| SMILES | C1C(C(=O)NC1=O)C2=CNC3=C2C=C(C=C3)F |
Computed by PubChem (NCBI)
Synonyms:
3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione, 2,5-Pyrrolidinedione, 3-(5-fluoro-1H-indol-3-yl)-, Indoleamine 2,3-Dioxygenase Inhibitor PF-06840003, 3-(5-fluoro-indol-3-yl)-pyrrolidine-2,5-dione, orb1225770, orb1302966, MXKLDYKORJEOPR-UHFFFAOYSA-N, s8657, 3a?5-Fluoroa?Ha'indol-3-yl)pyrrolidine-2,5-dione, 3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione