Products 198474-05-4
CAS 198474-05-4 appears in our catalog under these names: PF-06840003, PF-06840003/ 99.89% (existing batch purity), PF–06840003 (EOS200271), PF 06840003, PF-06840003 99%. Offered by: TRC, TargetMol, GLPBio, Biosynth, Ambeed. Available pack sizes: 1g, 2mg, 5mg, 10mg, 25mg, 50mg, 100mg, 1mg.
Pf-06840003 is iDO1 Inhibitor PF-06840003 is an orally available hydroxyamidine and inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with potential immunomodulating and antineoplastic activities. Upon administration, IDO1 inhibitor PF-06840003 targets and binds to IDO1, an enzyme responsible for the oxidation of tryptophan into kynurenine.
Source: ChEBI
| Molecular formula | C12H9FN2O2 |
|---|---|
| Molecular weight | 232.21 g/mol |
| IUPAC name | 3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione |
| InChIKey | MXKLDYKORJEOPR-UHFFFAOYSA-N |
| SMILES | C1C(C(=O)NC1=O)C2=CNC3=C2C=C(C=C3)F |
Computed by PubChem (NCBI)
Synonyms:
3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione, 2,5-Pyrrolidinedione, 3-(5-fluoro-1H-indol-3-yl)-, Indoleamine 2,3-Dioxygenase Inhibitor PF-06840003, 3-(5-fluoro-indol-3-yl)-pyrrolidine-2,5-dione, orb1225770, orb1302966, MXKLDYKORJEOPR-UHFFFAOYSA-N, s8657, 3a?5-Fluoroa?Ha'indol-3-yl)pyrrolidine-2,5-dione, 3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione