PLpro inhibitor, 99.88%
cas: 1093070-14-4 — see every product listed under this CAS number, including other names
PLpro inhibitor, 99.88% (CAS 1093070-14-4) is a chemical reagent available from Chemat. Available pack sizes: 50 mg, 10 mg, 5 mg, 1 mg, 100 mg, 10mM/1mL. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-17542-50 mg |
| cas | 1093070-14-4 |
| size | 50 mg |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 50 mg | 4819.73 Pln | |
| MedChemExpress | 10 mg | 1750.04 Pln | |
| MedChemExpress | 5 mg | 1127.75 Pln | |
| MedChemExpress | 1 mg | 528.67 Pln | |
| MedChemExpress | 100 mg | 6598.38 Pln | |
| MedChemExpress | 10mM/1mL | 1229.92 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.88% |
KOM70144 is a benzamide that is GRL-0617 in which one of the hydrogen's of the primary amino group is replaced by an acetyl group. It an inhibitor of SARS-CoV and SARS-CoV-2 papain-like protease (PLpro) with an IC50 of 2.6 M and 5.0 M, respectively. It also inhibits SARS-CoV and SARS-CoV-2 infection of Vero E6 cells in vitro (EC50 values are 13.1 and 21 M, respectively). It has a role as an anticoronaviral agent and a protease inhibitor. It is a secondary carboxamide, a member of acetamides, a member of benzamides and a member of naphthalenes. It is functionally related to a GRL-0617.
Source: ChEBI
| Molecular formula | C22H22N2O2 |
|---|---|
| Molecular weight | 346.4 g/mol |
| IUPAC name | 5-acetamido-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide |
| InChIKey | KGPYBLOBHQLIET-OAHLLOKOSA-N |
| SMILES | CC1=C(C=C(C=C1)NC(=O)C)C(=O)N[C@H](C)C2=CC=CC3=CC=CC=C32 |
Computed by PubChem (NCBI)
Synonyms:
(R)-5-acetamido-2-methyl-N-(1-(naphthalen-1-yl)ethyl)benzamide, 5-(acetylamino)-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]benzamide, 5-N-Acetylamino-2-methyl-N-[(R)-1-(1-naphthyl)ethyl]benzamide, 5-acetamido-2-methyl-N-((1R)-1-(naphthalen-1-yl)ethyl)benzamide, 5-N-acetylamino-2-methyl-N-((R)-1-(1-naphthyl)ethyl)benzamide, 5-(Acetylamino)-2-methyl-N-((1R)-1-(1-naphthalenyl)ethyl)benzamide, PLpro inhibitor, 5-acetamido-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, PLpro inhibitor 6, orb1219969