cas: 937272-79-2 — see every product listed under this CAS number, including other names
Pacritinib (Standard) (CAS 937272-79-2) is a chemical reagent available from Chemat. Available pack sizes: 25 mg, 50 mg, 5 mg, 10 mg, 100 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-16379R-25 mg |
| cas | 937272-79-2 |
| size | 25 mg |
| availability | Get quote |
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| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 25 mg | 2539.52 Pln | |
| MedChemExpress | 50 mg | 3746.96 Pln | |
| MedChemExpress | 5 mg | 960.56 Pln | |
| MedChemExpress | 10 mg | 1462.12 Pln | |
| MedChemExpress | 100 mg | 5562.77 Pln |
| delivery time | over 3 weeks |
|---|---|
| purity | no data |
Pacritinib is an azamacrocycle with formula C28H32N4O3. It is a Janus kinase inhibitor and its citrate salt is approved for the treatment of intermediate or high risk, primary or secondary myelofibrosis. It has a role as an antineoplastic agent, an anti-inflammatory agent, an apoptosis inducer and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a member of benzenes, a cyclic ether, a member of pyrrolidines and an azamacrocycle. It is a conjugate base of a pacritinib(1+).
Source: ChEBI
| Molecular formula | C28H32N4O3 |
|---|---|
| Molecular weight | 472.6 g/mol |
| IUPAC name | (16E)-11-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(24),2(27),3,5,8(26),9,11,16,21(25),22-decaene |
| InChIKey | HWXVIOGONBBTBY-ONEGZZNKSA-N |
| SMILES | C1CCN(C1)CCOC2=C3COC/C=C/COCC4=CC(=CC=C4)C5=NC(=NC=C5)NC(=C3)C=C2 |
Computed by PubChem (NCBI)