Pacritinib
cas: 937272-79-2 — see every product listed under this CAS number, including other names
Pacritinib (CAS 937272-79-2) is a chemical reagent available from Chemat. Available pack sizes: 200mg, 1mg, 5mg, 500μg, 50mg, 25mg. Offered by: TRC, GLPBio, Biosynth.
| brand | TRC |
|---|---|
| catalog number | TRC-P133700-200MG |
| cas | 937272-79-2 |
| size | 200mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| TRC | 200mg | price on request | |
| GLPBio | 1mg | 948.08 Pln | |
| GLPBio | 5mg | 1271.03 Pln | |
| GLPBio | 500μg | 695.33 Pln | |
| Biosynth | 50mg | price on request | |
| Biosynth | 25mg | price on request |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Pacritinib is an azamacrocycle with formula C28H32N4O3. It is a Janus kinase inhibitor and its citrate salt is approved for the treatment of intermediate or high risk, primary or secondary myelofibrosis. It has a role as an antineoplastic agent, an anti-inflammatory agent, an apoptosis inducer and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a member of benzenes, a cyclic ether, a member of pyrrolidines and an azamacrocycle. It is a conjugate base of a pacritinib(1+).
Source: ChEBI
| Molecular formula | C28H32N4O3 |
|---|---|
| Molecular weight | 472.6 g/mol |
| IUPAC name | (16E)-11-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(24),2(27),3,5,8(26),9,11,16,21(25),22-decaene |
| InChIKey | HWXVIOGONBBTBY-ONEGZZNKSA-N |
| SMILES | C1CCN(C1)CCOC2=C3COC/C=C/COCC4=CC(=CC=C4)C5=NC(=NC=C5)NC(=C3)C=C2 |
Computed by PubChem (NCBI)