Pacritinib (SB1518)
cas: 937272-79-2 — see every product listed under this CAS number, including other names
Pacritinib (SB1518) (CAS 937272-79-2) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 25mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC14676-10 |
| cas | 937272-79-2 |
| size | 10mg |
Need more information?
Ask us about this product — we're happy to help.
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 1341.24 Pln | |
| GLPBio | 25mg | 2108.84 Pln | |
| GLPBio | 5mg | 1046.37 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 1331.88 Pln | |
| GLPBio | 50mg | 3658.09 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Pacritinib is an azamacrocycle with formula C28H32N4O3. It is a Janus kinase inhibitor and its citrate salt is approved for the treatment of intermediate or high risk, primary or secondary myelofibrosis. It has a role as an antineoplastic agent, an anti-inflammatory agent, an apoptosis inducer and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a member of benzenes, a cyclic ether, a member of pyrrolidines and an azamacrocycle. It is a conjugate base of a pacritinib(1+).
Source: ChEBI
| Molecular formula | C28H32N4O3 |
|---|---|
| Molecular weight | 472.6 g/mol |
| IUPAC name | (16E)-11-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(24),2(27),3,5,8(26),9,11,16,21(25),22-decaene |
| InChIKey | HWXVIOGONBBTBY-ONEGZZNKSA-N |
| SMILES | C1CCN(C1)CCOC2=C3COC/C=C/COCC4=CC(=CC=C4)C5=NC(=NC=C5)NC(=C3)C=C2 |
Computed by PubChem (NCBI)