Rofecoxib - Bio-X â„¢
cas: 162011-90-7 — see every product listed under this CAS number, including other names
Rofecoxib - Bio-X â„¢ (CAS 162011-90-7) is a chemical reagent available from Chemat. Available pack sizes: 100mg. Offered by: Biosynth.
| brand | Biosynth |
|---|---|
| catalog number | BR164362-100mg |
| cas | 162011-90-7 |
| size | 100mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Biosynth | 100mg | price on request |
properties
| category | Life Sciences |
|---|---|
| sub-category 1 | Ligands |
| sub-category 2 | Enzyme Modulators |
| purity | No data |
| delivery time | 1-2 weeks |
Rofecoxib is a butenolide that is furan-2(5H)-one substituted by a phenyl group at position 3 and by a p-(methylsulfonyl)phenyl group at position 4. A selective cyclooxygenase 2 inhibitor, it was used from 1999 to 2004 for the treatment of ostoarthritis, but was withdrawn following concerns about an associated increased risk of heart attack and stroke. It has a role as a non-steroidal anti-inflammatory drug, an analgesic and a cyclooxygenase 2 inhibitor. It is a sulfone and a butenolide.
Source: ChEBI
| Molecular formula | C17H14O4S |
|---|---|
| Molecular weight | 314.4 g/mol |
| IUPAC name | 3-(4-methylsulfonylphenyl)-4-phenyl-2H-furan-5-one |
| InChIKey | RZJQGNCSTQAWON-UHFFFAOYSA-N |
| SMILES | CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=CC=C3 |
Computed by PubChem (NCBI)
Synonyms:
rofecoxib, Vioxx, Ceoxx, 4-(4-(Methylsulfonyl)phenyl)-3-phenylfuran-2(5H)-one, 4-[4-(methylsulfonyl)phenyl]-3-phenylfuran-2(5H)-one, Vioxx Dolor, 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone, rofecoxibum, 3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone, 4-(4-(Methylsulfonyl)phenyl)-3-phenyl-2(5H)-furanone