Rofecoxib

cas: 162011-90-7 — see every product listed under this CAS number, including other names

Rofecoxib (CAS 162011-90-7) is a chemical reagent available from Chemat. Available pack sizes: on request, 100mg, 250mg, 10mM (in 1ml dmso), 10g, 5g, 25g, 100g. Offered by: Chemat Brand, GLPBio, Biosynth, Thermo Scientific (Acros).

brandChemat Brand
catalog numberAO-R0077.00
cas162011-90-7
sizeon request
availability In stock
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Available pack sizes

brand size price
Chemat Brand on request price on request
Chemat Brand on request price on request
GLPBio 100mg 601.72 Pln
GLPBio 250mg 826.38 Pln
GLPBio 10mM (in 1ml dmso) 615.76 Pln
Biosynth 10g price on request
Biosynth 5g price on request
Thermo Scientific (Acros) 250MG 944.34 Pln
Biosynth 25g price on request
Biosynth 100g price on request
Biosynth 50g price on request
HPC Standards 1x10mg 488.86 Pln

properties

delivery timeTo be confirmed by Chemat
purityNo data
Structural formula: {0} (CAS {1})

Rofecoxib is a butenolide that is furan-2(5H)-one substituted by a phenyl group at position 3 and by a p-(methylsulfonyl)phenyl group at position 4. A selective cyclooxygenase 2 inhibitor, it was used from 1999 to 2004 for the treatment of ostoarthritis, but was withdrawn following concerns about an associated increased risk of heart attack and stroke. It has a role as a non-steroidal anti-inflammatory drug, an analgesic and a cyclooxygenase 2 inhibitor. It is a sulfone and a butenolide.

Source: ChEBI

Identity
Molecular formulaC17H14O4S
Molecular weight314.4 g/mol
IUPAC name3-(4-methylsulfonylphenyl)-4-phenyl-2H-furan-5-one
InChIKeyRZJQGNCSTQAWON-UHFFFAOYSA-N
SMILESCS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=CC=C3

Computed by PubChem (NCBI)

Synonyms: rofecoxib, Vioxx, Ceoxx, 4-(4-(Methylsulfonyl)phenyl)-3-phenylfuran-2(5H)-one, 4-[4-(methylsulfonyl)phenyl]-3-phenylfuran-2(5H)-one, Vioxx Dolor, 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone, rofecoxibum, 3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone, 4-(4-(Methylsulfonyl)phenyl)-3-phenyl-2(5H)-furanone
Related forms of this compound
3-(4-methylsulfonylphenyl)-4-(2,3,4,5,6-pentadeuteriophenyl)-2H-furan-5-one C17H14O4S
Isomers (same molecular formula)
2-(6,11-dioxo-5H-benzo[b][1]benzothiepin-3-yl)propanoic acid C17H14O4S

Also listed as

Vioxx, >95% (HPLC) TRC CAS 162011-90-7
Rofecoxib, >98.0%(GC) TCI CAS 162011-90-7
Rofecoxib - Bio-X â„¢ Biosynth CAS 162011-90-7
Rofecoxib, 99.00% Chemat CAS 162011-90-7
Rofecoxib 98% Ambeed CAS 162011-90-7
4-(4-(Methylsulfonyl)phenyl)-3-phenylfuran-2(5H)-one, 98%, 98% Chemat CAS 162011-90-7
4-(4-(Methylsulfonyl)phenyl)-3-phenylfuran-2(5H)-one, 98% Chemat CAS 162011-90-7
Rofecoxib, 99.89% MedChemExpress CAS 162011-90-7
Rofecoxib (Standard) MedChemExpress CAS 162011-90-7
4-[4-(Methylsulfonyl)phenyl]-3-phenylfuran-2(5H)-one, 99%(LC-MS),RG Fluorochem CAS 162011-90-7