Simurosertib (Standard)
cas: 1330782-76-7 — see every product listed under this CAS number, including other names
Simurosertib (Standard) (CAS 1330782-76-7) is a chemical reagent available from Chemat. Available pack sizes: Get quote. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-100888R-Get quote |
| cas | 1330782-76-7 |
| size | Get quote |
| availability | Get quote |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | Get quote | price on request |
properties
| delivery time | to confirm by Chemat |
|---|---|
| purity | no data |
Simurosertib is an orally bioavailable inhibitor of cell division cycle 7 (cell division cycle 7-related protein kinase; CDC7), with potential antineoplastic activity. Upon administration, simurosertib binds to and inhibits CDC7; this prevents the initiation of DNA replication during mitosis, which causes cell cycle arrest and induces apoptosis. This inhibits cell growth in CDC7-overexpressing tumor cells.
Source: ChEBI
| Molecular formula | C17H19N5OS |
|---|---|
| Molecular weight | 341.4 g/mol |
| IUPAC name | 2-[(2S)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1H-pyrazol-4-yl)-3H-thieno[3,2-d]pyrimidin-4-one |
| InChIKey | XGVXKJKTISMIOW-ZDUSSCGKSA-N |
| SMILES | CC1=C(C=NN1)C2=CC3=C(S2)C(=O)NC(=N3)[C@@H]4CC5CCN4CC5 |
Computed by PubChem (NCBI)