Simurosertib, 99.94%
cas: 1330782-76-7 — see every product listed under this CAS number, including other names
Simurosertib, 99.94% (CAS 1330782-76-7) is a chemical reagent available from Chemat. Available pack sizes: 5 mg, 10 mg, 25 mg, 50 mg, 2 mg, 10mM/1mL, 100 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-100888-5 mg |
| cas | 1330782-76-7 |
| size | 5 mg |
| availability | Get quote |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 5 mg | 1183.48 Pln | |
| MedChemExpress | 10 mg | 1587.50 Pln | |
| MedChemExpress | 25 mg | 2613.83 Pln | |
| MedChemExpress | 50 mg | 3565.85 Pln | |
| MedChemExpress | 2 mg | 742.30 Pln | |
| MedChemExpress | 10mM/1mL | 1290.29 Pln | |
| MedChemExpress | 100 mg | 4880.10 Pln |
properties
| delivery time | over 3 weeks |
|---|---|
| purity | 99.94% |
Simurosertib is an orally bioavailable inhibitor of cell division cycle 7 (cell division cycle 7-related protein kinase; CDC7), with potential antineoplastic activity. Upon administration, simurosertib binds to and inhibits CDC7; this prevents the initiation of DNA replication during mitosis, which causes cell cycle arrest and induces apoptosis. This inhibits cell growth in CDC7-overexpressing tumor cells.
Source: ChEBI
| Molecular formula | C17H19N5OS |
|---|---|
| Molecular weight | 341.4 g/mol |
| IUPAC name | 2-[(2S)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1H-pyrazol-4-yl)-3H-thieno[3,2-d]pyrimidin-4-one |
| InChIKey | XGVXKJKTISMIOW-ZDUSSCGKSA-N |
| SMILES | CC1=C(C=NN1)C2=CC3=C(S2)C(=O)NC(=N3)[C@@H]4CC5CCN4CC5 |
Computed by PubChem (NCBI)