Simurosertib (TAK–931)
cas: 1330782-76-7 — see every product listed under this CAS number, including other names
Simurosertib (TAK–931) (CAS 1330782-76-7) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 10mM (in 1ml dmso), 2mg, 5mg, 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC32930-10 |
| cas | 1330782-76-7 |
| size | 10mg |
Need more information?
Ask us about this product — we're happy to help.
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 1973.11 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 1355.28 Pln | |
| GLPBio | 2mg | 1060.41 Pln | |
| GLPBio | 5mg | 1383.36 Pln | |
| GLPBio | 50mg | 5132.44 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Simurosertib is an orally bioavailable inhibitor of cell division cycle 7 (cell division cycle 7-related protein kinase; CDC7), with potential antineoplastic activity. Upon administration, simurosertib binds to and inhibits CDC7; this prevents the initiation of DNA replication during mitosis, which causes cell cycle arrest and induces apoptosis. This inhibits cell growth in CDC7-overexpressing tumor cells.
Source: ChEBI
| Molecular formula | C17H19N5OS |
|---|---|
| Molecular weight | 341.4 g/mol |
| IUPAC name | 2-[(2S)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1H-pyrazol-4-yl)-3H-thieno[3,2-d]pyrimidin-4-one |
| InChIKey | XGVXKJKTISMIOW-ZDUSSCGKSA-N |
| SMILES | CC1=C(C=NN1)C2=CC3=C(S2)C(=O)NC(=N3)[C@@H]4CC5CCN4CC5 |
Computed by PubChem (NCBI)