Products 1330782-76-7

CAS 1330782-76-7 appears in our catalog under these names: Simurosertib/ 99.93% (existing batch purity), Simurosertib (TAK–931), Simurosertib, Simurosertib 99%, Simurosertib, 99%, 99%. Offered by: TargetMol, GLPBio, Biosynth, Ambeed, Chemat. Available pack sizes: 1mg, 2mg, 5mg, 10mg, 25mg, 50mg, 100mg, 10mM (in 1ml dmso).

Simurosertib/ 99.93% (existing batch purity)
TargetMol
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 7
from 624.84
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Simurosertib (TAK–931)
GLPBio
  • size: 10mg, 10mM (in 1ml dmso), 2mg, 5mg
  • Variants: 5
from 1060.41
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Simurosertib
Biosynth
  • size: 25mg, 10mg, 50mg
  • Variants: 3
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Simurosertib 99%
Ambeed
  • size: 1g, 2mg, 5mg, 10mg
  • Variants: 8
from 453.81
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Simurosertib, 99%, 99%
Chemat
  • size: 2mg, 10mg, 25mg, 50mg
  • Variants: 8
from 280.40
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Simurosertib, 99.94%
MedChemExpress
  • size: 5 mg, 10 mg, 25 mg, 50 mg
  • Variants: 7
from 742.30
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Simurosertib (Standard)
MedChemExpress
  • size: Get quote
  • Variants: 1
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Structural formula: {0} (CAS {1})

Simurosertib is an orally bioavailable inhibitor of cell division cycle 7 (cell division cycle 7-related protein kinase; CDC7), with potential antineoplastic activity. Upon administration, simurosertib binds to and inhibits CDC7; this prevents the initiation of DNA replication during mitosis, which causes cell cycle arrest and induces apoptosis. This inhibits cell growth in CDC7-overexpressing tumor cells.

Source: ChEBI

Identity
Molecular formulaC17H19N5OS
Molecular weight341.4 g/mol
IUPAC name2-[(2S)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1H-pyrazol-4-yl)-3H-thieno[3,2-d]pyrimidin-4-one
InChIKeyXGVXKJKTISMIOW-ZDUSSCGKSA-N
SMILESCC1=C(C=NN1)C2=CC3=C(S2)C(=O)NC(=N3)[C@@H]4CC5CCN4CC5

Computed by PubChem (NCBI)

Synonyms: Simurosertib, Tak 931, simurosertibum, Cell Division Cycle 7 Inhibitor TAK-931, Simurosertib [USAN], Simurosertib (USAN/INN), SIMUROSERTIB [INN], Simurosertib (TAK-931)?, SIMUROSERTIB [WHO-DD], orb1309184
Related forms of this compound
2-[(2R)-1-azabicyclo[2.2.2]octan-2-yl]-6-(5-methyl-1H-pyrazol-4-yl)-3H-thieno[3,2-d]pyrimidin-4-one C17H19N5OS