TW-37 98%

cas: 877877-35-5 — see every product listed under this CAS number, including other names

TW-37 98% (CAS 877877-35-5) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 50mg, 100mg, 250mg. Offered by: Ambeed.

brandAmbeed
catalog numberA252493-10mg
cas877877-35-5
size10mg
Documents: Safety Data Sheet (MSDS)
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Available pack sizes

brand size price
Ambeed 10mg 681.88 Pln
Ambeed 50mg 1799.94 Pln
Ambeed 100mg 3524.31 Pln
Ambeed 250mg 7390.25 Pln

properties

purity98%
delivery time 2-3 weeks
ambeed catalog no.A252493
Structural formula: {0} (CAS {1})

TW-37 is a secondary carboxamide resulting from the formal condensation of the carboxy group of 2,3,4-trihydroxy-5-[2-(propan-2-yl)benzyl]benzoic acid with the amino group of 4-[(2-tert-butylphenyl)sulfonyl]aniline. It is a potent inhibitor of Bcl-2 family of proteins (Ki = 260, 290 and 1110 nM for Mcl-1, Bcl-2 and Bcl-xL). It has a role as a radiosensitizing agent, a B-cell lymphoma 2 inhibitor, an antineoplastic agent, an angiogenesis inhibitor and an apoptosis inducer. It is a secondary carboxamide, a member of benzamides, a benzenetriol and a sulfone.

Source: ChEBI

Identity
Molecular formulaC33H35NO6S
Molecular weight573.7 g/mol
IUPAC nameN-[4-(2-tert-butylphenyl)sulfonylphenyl]-2,3,4-trihydroxy-5-[(2-propan-2-ylphenyl)methyl]benzamide
InChIKeyPQAPVTKIEGUPRN-UHFFFAOYSA-N
SMILESCC(C)C1=CC=CC=C1CC2=CC(=C(C(=C2O)O)O)C(=O)NC3=CC=C(C=C3)S(=O)(=O)C4=CC=CC=C4C(C)(C)C

Computed by PubChem (NCBI)

Synonyms: tw 37, tw-37?, orb1223766, orb1300906, s1121

Also listed as

N-{4-[(2-tert-butylbenzene)sulfonyl]phenyl}-2,3,4-trihydroxy-5-[(2-isopropylphenyl)methyl]benzamide, 95% Combi-blocks CAS 877877-35-5
TW–37 GLPBio CAS 877877-35-5
TW-37/ 98% TargetMol CAS 877877-35-5
N-[4-(2-tert-Butylphenylsulfonyl)phenyl]-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide, 98%, 98% Chemat CAS 877877-35-5
TW-37, 99.50% MedChemExpress CAS 877877-35-5