CAS 171596-29-5 appears in our catalog under these names: Tadalafil, 98%, Tadalafil, Tadalafil, >95% (HPLC), Tadalafil 1.0 mg/ml in Acetonitrile, Tadalafil/ 99.53% (existing batch purity). Offered by: Combi-blocks, Chemat Brand, TRC, Mikromol, LoGiCal. Available pack sizes: 25g, 500g, 5g, 100g, 1g, on request, 100mg, 10mg.
Tadalafil is a pyrazinopyridoindole that is 2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione substituted at position 2 by a methyl group and at position 6 by a 1,3-benzodioxol-5-yl group (the 6R,12aR-diastereomer). A phosphodiesterase V inhibitor inhibitor, currently marketed in pill form for treating erectile dysfunction under the name Cialis; and under the name Adcirca for the treatment of pulmonary arterial hypertension. It has a role as a vasodilator agent and an EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor. It is a member of benzodioxoles and a pyrazinopyridoindole.
Source: ChEBI
| Molecular formula | C22H19N3O4 |
|---|---|
| Molecular weight | 389.4 g/mol |
| IUPAC name | (2R,8R)-2-(1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione |
| InChIKey | WOXKDUGGOYFFRN-IIBYNOLFSA-N |
| SMILES | CN1CC(=O)N2[C@@H](C1=O)CC3=C([C@H]2C4=CC5=C(C=C4)OCO5)NC6=CC=CC=C36 |
Computed by PubChem (NCBI)