Tideglusib, >95% (HPLC)

cas: 865854-05-3 — see every product listed under this CAS number, including other names

Tideglusib, >95% (HPLC) (CAS 865854-05-3) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 10mg, 50mg. Offered by: TRC.

brandTRC
catalog numberTRC-T438700-100MG
cas865854-05-3
size100mg
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Available pack sizes

brand size price
TRC 100mg price on request
TRC 10mg price on request
TRC 50mg price on request

properties

purity>95% (HPLC)
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Tideglusib is a member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a naphthalen-1-yl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta) and has neuroprotective effects. Currently under clinical investigation for the treatment of Alzheimer's disease and progressive supranuclear palsy. It has a role as a neuroprotective agent, an anti-inflammatory agent, an apoptosis inducer and an EC 2.7.11.26 (tau-protein kinase) inhibitor. It is a member of benzenes, a member of naphthalenes and a thiadiazolidine.

Source: ChEBI

Identity
Molecular formulaC19H14N2O2S
Molecular weight334.4 g/mol
IUPAC name4-benzyl-2-naphthalen-1-yl-1,2,4-thiadiazolidine-3,5-dione
InChIKeyPMJIHLSCWIDGMD-UHFFFAOYSA-N
SMILESC1=CC=C(C=C1)CN2C(=O)N(SC2=O)C3=CC=CC4=CC=CC=C43

Computed by PubChem (NCBI)

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