Tideglusib

cas: 865854-05-3 — see every product listed under this CAS number, including other names

Tideglusib (CAS 865854-05-3) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 200mg, 5mg, 50mg, 0,5g, 0,25g, 1g, 2g. Offered by: GLPBio, Biosynth.

brandGLPBio
catalog numberGC14465-10
cas865854-05-3
size10mg
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Available pack sizes

brand size price
GLPBio 10mg 681.29 Pln
GLPBio 200mg 1584.63 Pln
GLPBio 5mg 714.05 Pln
GLPBio 50mg 831.06 Pln
Biosynth 0,5g price on request
Biosynth 0,25g price on request
Biosynth 1g price on request
Biosynth 2g price on request
Biosynth 5g price on request

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Tideglusib is a member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a naphthalen-1-yl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta) and has neuroprotective effects. Currently under clinical investigation for the treatment of Alzheimer's disease and progressive supranuclear palsy. It has a role as a neuroprotective agent, an anti-inflammatory agent, an apoptosis inducer and an EC 2.7.11.26 (tau-protein kinase) inhibitor. It is a member of benzenes, a member of naphthalenes and a thiadiazolidine.

Source: ChEBI

Identity
Molecular formulaC19H14N2O2S
Molecular weight334.4 g/mol
IUPAC name4-benzyl-2-naphthalen-1-yl-1,2,4-thiadiazolidine-3,5-dione
InChIKeyPMJIHLSCWIDGMD-UHFFFAOYSA-N
SMILESC1=CC=C(C=C1)CN2C(=O)N(SC2=O)C3=CC=CC4=CC=CC=C43

Computed by PubChem (NCBI)

Synonyms: Tideglusib, 4-Benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione, tideglusibum, Zentylor, Nypta, Zentylor nypta, 4-benzyl-2-(a-naphtyl)-1,2,4-thiadiazolidine-3,5-dione, 4-benzyl-2-(naphthalene-1-yl)-1,2,4-thiadiazolidine-3,5-dione, Tideglusib [INN], Tideglusib(NP-031112)
Related forms of this compound
4-benzyl-2-naphthalen-1-yl-1,2,4-thiadiazolidine-3,5-dione C19H14N2O2S
Isomers (same molecular formula)
2-(2,5-dioxopyrrol-1-yl)-6-phenyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carbonitrile C19H14N2O2S
N-quinolin-8-ylnaphthalene-2-sulfonamide C19H14N2O2S

Also listed as

Tideglusib, >95% (HPLC) TRC CAS 865854-05-3
Tideglusib/ 98.89% (existing batch purity) TargetMol CAS 865854-05-3
Tideglusib, 98%, 98% Chemat CAS 865854-05-3
Tideglusib, 99.76% MedChemExpress CAS 865854-05-3
Tideglusib, 98% Fluorochem CAS 865854-05-3