Products 865854-05-3
CAS 865854-05-3 appears in our catalog under these names: Tideglusib, >95% (HPLC), Tideglusib, Tideglusib/ 98.89% (existing batch purity), Tideglusib 98%, Tideglusib, 98%, 98%. Offered by: TRC, GLPBio, TargetMol, Biosynth, Ambeed. Available pack sizes: 100mg, 10mg, 50mg, 200mg, 5mg, 25mg, 500mg, 0,5g.
Tideglusib is a member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a naphthalen-1-yl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta) and has neuroprotective effects. Currently under clinical investigation for the treatment of Alzheimer's disease and progressive supranuclear palsy. It has a role as a neuroprotective agent, an anti-inflammatory agent, an apoptosis inducer and an EC 2.7.11.26 (tau-protein kinase) inhibitor. It is a member of benzenes, a member of naphthalenes and a thiadiazolidine.
Source: ChEBI
| Molecular formula | C19H14N2O2S |
|---|---|
| Molecular weight | 334.4 g/mol |
| IUPAC name | 4-benzyl-2-naphthalen-1-yl-1,2,4-thiadiazolidine-3,5-dione |
| InChIKey | PMJIHLSCWIDGMD-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)CN2C(=O)N(SC2=O)C3=CC=CC4=CC=CC=C43 |
Computed by PubChem (NCBI)