Tipiracil
cas: 183204-74-2 — see every product listed under this CAS number, including other names
Tipiracil (CAS 183204-74-2) is a chemical reagent available from Chemat. Available pack sizes: 2mg, 10mg, 100mg, 5mg, 50mg. Offered by: TargetMol, GLPBio.
| brand | TargetMol |
|---|---|
| catalog number | T60343-2mg |
| cas | 183204-74-2 |
| size | 2mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| TargetMol | 2mg | 571.74 Pln | |
| GLPBio | 10mg | 742.14 Pln | |
| GLPBio | 100mg | 1982.47 Pln | |
| GLPBio | 5mg | 643.84 Pln | |
| GLPBio | 50mg | 1355.28 Pln |
properties
| purity | No data |
|---|---|
| delivery time | approx. 26 days |
Tipiracil is a member of the class of pyrimidones that is uracil substituted by chloro and (2-iminopyrrolidin-1-yl)methyl groups at positions 5 and 6 respectively. Used (as the hydrochloride salt) in combination with trifluridine, a nucleoside metabolic inhibitor, for treatment of advanced/relapsed unresectable colorectal cancer. It has a role as an antineoplastic agent and an EC 2.4.2.4 (thymidine phosphorylase) inhibitor. It is a carboxamidine, an organochlorine compound, a member of pyrrolidines and a pyrimidone. It is functionally related to a uracil. It is a conjugate base of a tipiracil(1+).
Source: ChEBI
| Molecular formula | C9H11ClN4O2 |
|---|---|
| Molecular weight | 242.66 g/mol |
| IUPAC name | 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1H-pyrimidine-2,4-dione |
| InChIKey | QQHMKNYGKVVGCZ-UHFFFAOYSA-N |
| SMILES | C1CC(=N)N(C1)CC2=C(C(=O)NC(=O)N2)Cl |
Computed by PubChem (NCBI)
Synonyms:
Tipiracil, TPI (freebase), Tipiracilo, 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1H-pyrimidine-2,4-dione, 5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4-(1H,3H)-dione, 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1h,3h)-pyrimidinedione, tipiracilum, 5-chloro-6-((2-iminopyrrolidin-1-yl)methyl)-1H-pyrimidine-2,4-dione, 5-Chloro-6-[(2-iminopyrrolidin-1-yl)methyl]pyrimidine-2,4-(1H,3H)-dione, 5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dione