Products 183204-74-2
CAS 183204-74-2 appears in our catalog under these names: Tipiracil, Tipiracil, 99.98%, Tipiracil, 99%, 5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dione, 99%. Offered by: TargetMol, GLPBio, MedChemExpress, Ambeed, Chemat. Available pack sizes: 2mg, 10mg, 100mg, 5mg, 50mg, 5 mg, 200 mg, 100 mg.
Tipiracil is a member of the class of pyrimidones that is uracil substituted by chloro and (2-iminopyrrolidin-1-yl)methyl groups at positions 5 and 6 respectively. Used (as the hydrochloride salt) in combination with trifluridine, a nucleoside metabolic inhibitor, for treatment of advanced/relapsed unresectable colorectal cancer. It has a role as an antineoplastic agent and an EC 2.4.2.4 (thymidine phosphorylase) inhibitor. It is a carboxamidine, an organochlorine compound, a member of pyrrolidines and a pyrimidone. It is functionally related to a uracil. It is a conjugate base of a tipiracil(1+).
Source: ChEBI
| Molecular formula | C9H11ClN4O2 |
|---|---|
| Molecular weight | 242.66 g/mol |
| IUPAC name | 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1H-pyrimidine-2,4-dione |
| InChIKey | QQHMKNYGKVVGCZ-UHFFFAOYSA-N |
| SMILES | C1CC(=N)N(C1)CC2=C(C(=O)NC(=O)N2)Cl |
Computed by PubChem (NCBI)
Synonyms:
Tipiracil, TPI (freebase), Tipiracilo, 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1H-pyrimidine-2,4-dione, 5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4-(1H,3H)-dione, 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1h,3h)-pyrimidinedione, tipiracilum, 5-chloro-6-((2-iminopyrrolidin-1-yl)methyl)-1H-pyrimidine-2,4-dione, 5-Chloro-6-[(2-iminopyrrolidin-1-yl)methyl]pyrimidine-2,4-(1H,3H)-dione, 5-Chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dione