Products 1971920-73-6

Name: Tolebrutinib/ 99.2% (existing batch purity)
Availability: InStock

CAS 1971920-73-6 appears in our catalog under these names: Tolebrutinib/ 99.2% (existing batch purity), Tolebrutinib, Tolebrutinib 97%, (R)-1-(1-Acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, 98%, 98%, Tolebrutinib, 99.79%. Offered by: TargetMol, GLPBio, Biosynth, Ambeed, Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 250mg, 1g.

Tolebrutinib (SAR442168) is a potent, selective, orally active and brain-penetrant inhibitor of Bruton tyrosine kinase (BTK), with IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively. Tolebrutinib exhibits efficacy in central nervous system immunity. Tolebrutinib can be used for the research of multiple sclerosis (MS).

Source: ChEBI

Identity
Molecular formula	C₂₆H₂₅N₅O₃
Molecular weight	455.5 g/mol
IUPAC name	4-amino-3-(4-phenoxyphenyl)-1-[(3R)-1-prop-2-enoylpiperidin-3-yl]imidazo[4,5-c]pyridin-2-one
InChIKey	KOEUOFPEZFUWRF-LJQANCHMSA-N
SMILES	C=CC(=O)N1CCC[C@H](C1)N2C3=C(C(=NC=C3)N)N(C2=O)C4=CC=C(C=C4)OC5=CC=CC=C5

Computed by PubChem (NCBI)

Synonyms: Tolebrutinib, Tolebrutinib [INN], Tolebrutinib [USAN], TOLEBRUTINIB [WHO-DD], example 3 [WO2016196840A1], example 3 (WO2016196840A1), BTK Inhibitor SAR442168, Bruton's Tyrosine Kinase Inhibitor SAR442168, c]pyridin-2-one, Cenrifki

Products 1971920-73-6

Tolebrutinib/ 99.2% (existing batch purity)

Tolebrutinib

Tolebrutinib 97%

(R)-1-(1-Acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one, 98%, 98%

Tolebrutinib, 99.79%

Isomers (same molecular formula)