Tovorafenib 99%

cas: 1096708-71-2 — see every product listed under this CAS number, including other names

Tovorafenib 99% (CAS 1096708-71-2) is a chemical reagent available from Chemat. Available pack sizes: 1g, 1mg, 2mg, 5mg, 10mg, 25mg, 50mg, 100mg. Offered by: Ambeed.

brandAmbeed
catalog numberA107516-1g
cas1096708-71-2
size1g
Documents: Safety Data Sheet (MSDS)
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Available pack sizes

brand size price
Ambeed 1g 28633.44 Pln
Ambeed 1mg 236.88 Pln
Ambeed 2mg 320.31 Pln
Ambeed 5mg 565.06 Pln
Ambeed 10mg 954.44 Pln
Ambeed 25mg 2044.69 Pln
Ambeed 50mg 2929.12 Pln
Ambeed 100mg 4531.12 Pln
Ambeed 250mg 8992.25 Pln

properties

purity99%
delivery time 1-2 weeks
ambeed catalog no.A107516
Structural formula: {0} (CAS {1})

TAK-580 is a 1,3-thiazolecarboxamide that is 2-[(1R)-1-aminoethyl]-1,3-thiazole-5-carboxylic acid in which the carboxy group undergoes formal condensation with the amino group of 5-chloro-4-(trifluoromethyl)pyridin-2-amine and in which the amino group undergoes formal condensation with the carboxy group of 6-amino-5-chloropyrimidine-4-carboxylic acid. It is a pan-RAF kinase inhibitor which is currently in clinical development for the treatment of radiographically recurrent or progressive low-grade glioma in children and young adults. It has a role as an antineoplastic agent, an apoptosis inducer and a B-Raf inhibitor. It is a secondary carboxamide, an organofluorine compound, an aminopyrimidine, a chloropyridine, a pyrimidinecarboxamide and a 1,3-thiazolecarboxamide.

Source: ChEBI

Identity
Molecular formulaC17H12Cl2F3N7O2S
Molecular weight506.3 g/mol
IUPAC name2-[(1R)-1-[(6-amino-5-chloropyrimidine-4-carbonyl)amino]ethyl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide
InChIKeyVWMJHAFYPMOMGF-ZCFIWIBFSA-N
SMILESC[C@H](C1=NC=C(S1)C(=O)NC2=NC=C(C(=C2)C(F)(F)F)Cl)NC(=O)C3=C(C(=NC=N3)N)Cl

Computed by PubChem (NCBI)

Synonyms: Tovorafenib, Tak-580, OJEMDA, Tak 580, pan-RAF Kinase Inhibitor DAY101, Tovorafenib [USAN], C17H12Cl2F3N7O2S, QOP, Ojemda (TN), Tovorafenib [WHO-DD]

Also listed as

MLN 2480 GLPBio CAS 1096708-71-2
MLN2480 TRC CAS 1096708-71-2
TAK-580/ 99.25% (existing batch purity) TargetMol CAS 1096708-71-2
BIIB-024 Biosynth CAS 1096708-71-2
6-Amino-5-chloro-N-[(1R)-1-[5-[[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]amino]carbonyl]-2-thiazolyl]ethyl]-4-pyrimidinecarboxamide, 99%, 99% Chemat CAS 1096708-71-2
Tovorafenib, 99.89% MedChemExpress CAS 1096708-71-2