Varlitinib, 99%
cas: 845272-21-1 — see every product listed under this CAS number, including other names
Varlitinib, 99% (CAS 845272-21-1) is a chemical reagent available from Chemat. Available pack sizes: 250mg. Offered by: Ambeed.
| brand | Ambeed |
|---|---|
| catalog number | A621686-250mg |
| cas | 845272-21-1 |
| size | 250mg |
Need more information?
Ask us about this product — we're happy to help.
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Ambeed | 250mg | 7657.25 Pln |
properties
| purity | 99% |
|---|---|
| delivery time | 1-2 weeks |
Varlitinib is a member of the class of quinazolines that is quinazoline substituted by {3-chloro-4-[(1,3-thiazol-2-yl)methoxy]phenyl}amino and [(4R)-4-methyl-4,5-dihydro-1,3-oxazol-2-yl]amino groups at positions 4 and 6, respectively. It is a tyrosine kinase inhibitor of both ErbB-2 (Her-2/neu) and EGFR and has shown significant anti-tumour activity in preclinical models of human breast, lung, and epidermal carcinoma tumours. It has a role as an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor, an apoptosis inducer and an epidermal growth factor receptor antagonist. It is an aromatic ether, a quinazoline, an oxazoline, a member of 1,3-thiazoles, a substituted aniline, a secondary amino compound and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C22H19ClN6O2S |
|---|---|
| Molecular weight | 466.9 g/mol |
| IUPAC name | 4-N-[3-chloro-4-(1,3-thiazol-2-ylmethoxy)phenyl]-6-N-[(4R)-4-methyl-4,5-dihydro-1,3-oxazol-2-yl]quinazoline-4,6-diamine |
| InChIKey | UWXSAYUXVSFDBQ-CYBMUJFWSA-N |
| SMILES | C[C@@H]1COC(=N1)NC2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=NC=CS5)Cl |
Computed by PubChem (NCBI)