CAS 148642-42-6 appears in our catalog under these names: GR 127935 Hydrochloride Hydrate, >95% (HPLC), GR 127935 hydrochloride, GR 127935 hydrochloride, GR 127935 hydrochloride hydrate, GR 127935 hydrochloride, 98%, 98%. Offered by: TRC, TargetMol, GLPBio, Biosynth, Sigma-Aldrich. Available pack sizes: 10mg, 1mg, 5mg, 25mg, 50mg, 250mg, 100mg, 500mg.
GR 127935 hydrochloride is a hydrochloride obtained by reaction of GR 127935 with one equivalent of hydrochloric acid. Potent and selective 5-HT1B/1D receptor antagonist (pKi values are 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptors). Displays > 100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types. Centrally active following oral administration. It has a role as a serotonergic antagonist. It contains a GR 127935(1+).
Source: ChEBI
| Molecular formula | C29H32ClN5O3 |
|---|---|
| Molecular weight | 534.0 g/mol |
| IUPAC name | N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]-4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzamide;hydrochloride |
| InChIKey | SRVVUYIJVBLEJI-UHFFFAOYSA-N |
| SMILES | CC1=C(C=CC(=C1)C2=NOC(=N2)C)C3=CC=C(C=C3)C(=O)NC4=CC(=C(C=C4)OC)N5CCN(CC5)C.Cl |
Computed by PubChem (NCBI)