Products 162401-32-3

CAS 162401-32-3 appears in our catalog under these names: Roflumilast, 3,4-Bis(difluoromethoxy) Roflumilast, Roflumilast, >95% (HPLC), Roflumilast/ 99.64% (existing batch purity), Roflumilast, >98.0%(HPLC). Offered by: Chemat Brand, TRC, Mikromol, TargetMol, GLPBio. Available pack sizes: on request, 500mg, 250mg, 10mg, 1g, 5mg, 25mg, 50mg.

Roflumilast
Chemat Brand, Mikromol, GLPBio
  • size: on request, 250mg, 10mg, 25mg
  • Variants: 14
from 395.77
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3,4-Bis(difluoromethoxy) Roflumilast
TRC
  • size: 500mg
  • Variants: 1
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Roflumilast, >95% (HPLC)
TRC
  • size: 10mg, 1g, 5mg
  • Variants: 3
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Roflumilast/ 99.64% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 5
from 511.92
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Roflumilast, >98.0%(HPLC)
TCI
  • size: 250mg, 1g
  • Variants: 2
from 296.86
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Roflumilast - Bio-X â„¢
Biosynth
  • size: 10mg
  • Variants: 1
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Roflumilast 99%
Ambeed
  • size: 10mg, 250mg, 1g, 5g
  • Variants: 6
from 131.19
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3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide, 97%, 97%
Chemat
  • size: 1g, 5g, 25g
  • Variants: 3
from 150.80
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Roflumilast, 99.98%
MedChemExpress
  • size: 5 mg, 500 mg, 10 mg, 50 mg
  • Variants: 7
from 435.79
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Roflumilast (Standard)
MedChemExpress
  • size: 50 mg, 25 mg, 100 mg, 10 mg
  • Variants: 5
from 886.26
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Roflumilast, 97%
Fluorochem
  • size: 1g, 5g, 25g
  • Variants: 3
from 237.43
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3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide, 97%
Chemat
  • size: 250mg
  • Variants: 1
from 88.40
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Structural formula: {0} (CAS {1})

Roflumilast is a benzamide obtained by formal condensation of the carboxy group of 3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzoic acid with the amino group of 3,5-dichloropyridin-4-amine. Used for treatment of bronchial asthma and chronic obstructive pulmonary disease. It has a role as an anti-asthmatic drug and a phosphodiesterase IV inhibitor. It is a member of benzamides, an aromatic ether, an organofluorine compound, a chloropyridine and a member of cyclopropanes.

Source: ChEBI

Identity
Molecular formulaC17H14Cl2F2N2O3
Molecular weight403.2 g/mol
IUPAC name3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide
InChIKeyMNDBXUUTURYVHR-UHFFFAOYSA-N
SMILESC1CC1COC2=C(C=CC(=C2)C(=O)NC3=C(C=NC=C3Cl)Cl)OC(F)F

Computed by PubChem (NCBI)

Synonyms: Roflumilast, DAXAS, Daliresp, ZORYVE, roflumilastum, 3-cyclopropylmethoxy-4-difluoromethoxy-N-(3,5-di-chloropyrid-4-yl)benzamide, 3-Cyclopropylmethoxy-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide, C17H14Cl2F2N2O3, 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide, 1xmu
Related forms of this compound
N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-3-[(2,2,3,3-tetradeuteriocyclopropyl)methoxy]benzamide C17H14Cl2F2N2O3
N-(3,5-dichloro-4-pyridinyl)-3-[dideuterio-(1-deuteriocyclopropyl)methoxy]-4-(difluoromethoxy)benzamide C17H14Cl2F2N2O3
Isomers (same molecular formula)
4-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-3-(difluoromethoxy)benzamide C17H14Cl2F2N2O3
3-but-3-enoxy-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide C17H14Cl2F2N2O3