Products 260264-93-5
CAS 260264-93-5 appears in our catalog under these names: GI 254023X, GI 254023X, GI254023X/ 98.56% (existing batch purity), GI254023X 99%, Benzenepentanamide, N-[(1S)-2,2-dimethyl-1-[(methylamino)carbonyl]propyl]-α-[(1S)-1-(formylhydroxyamino)ethyl]-, (αR)-, 99%, 99%. Offered by: TRC, GLPBio, TargetMol, Biosynth, Ambeed. Available pack sizes: 500mg, 1mg, 2mg, 5mg, 10mg, 25mg, 50mg, 100mg.
GI254023X is a L-valine derivative that is 3-methyl-L-valine in which carboxy OH group is replaced by a methylnitrilo group and the one of the amino hydrogens is replaced by a (2R)-2-{(1S)-1-[formyl(hydroxy)amino]ethyl}-5-phenylpentanoyl group. It is a potent MMP9 and ADAM10 metalloprotease inhibitor with IC50 of 2.5 and 5.3 nM, respectively. It has a role as an antineoplastic agent, a matrix metalloproteinase inhibitor, an EC 3.4.24.* (metalloendopeptidase) inhibitor and an apoptosis inducer. It is an aldehyde, a member of hydroxylamines and a L-valine derivative.
Source: ChEBI
| Molecular formula | C21H33N3O4 |
|---|---|
| Molecular weight | 391.5 g/mol |
| IUPAC name | (2R)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-2-[(1S)-1-[formyl(hydroxy)amino]ethyl]-5-phenylpentanamide |
| InChIKey | GHVMTHKJUAOZJP-CGTJXYLNSA-N |
| SMILES | C[C@@H]([C@@H](CCCC1=CC=CC=C1)C(=O)N[C@H](C(=O)NC)C(C)(C)C)N(C=O)O |
Computed by PubChem (NCBI)