CAS 322-35-0 appears in our catalog under these names: 2-Amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide, 97%, Levodopa Impurity 8, Benserazide, 98.43%, Benserazide-d3. Offered by: Chemat Brand, Hubei YoungXin, MedChemExpress. Available pack sizes: on request, 10mg, 25mg, 50mg, 100mg, 200mg, 25 mg, 50 mg.
Benserazide is a carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone. It has a role as an antiparkinson drug, a dopaminergic agent and an EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor. It is a primary alcohol, a member of catechols, a carbohydrazide and a primary amino compound. It is a conjugate base of a benserazide(1+).
Source: ChEBI
| Molecular formula | C10H15N3O5 |
|---|---|
| Molecular weight | 257.24 g/mol |
| IUPAC name | 2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide |
| InChIKey | BNQDCRGUHNALGH-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O |
Computed by PubChem (NCBI)