Products 38194-50-2
CAS 38194-50-2 appears in our catalog under these names: Sulindac, min. 95 %, 50 g, Sulindac, min. 95 %, 2 g, (Z)-2-(5-Fluoro-2-methyl-1-(4-(methylsulfinyl)benzylidene)-1H-inden-3-yl)acetic acid, 98%, Sulindac, min. 95 %, 5 g, Sulindac. Offered by: Roth, Fluorochem, Chemat Brand, Mikromol, LoGiCal. Available pack sizes: 50g, 2g, 1g, 5g, 25g, 100g, on request, 500mg.
Sulindac is a monocarboxylic acid that is 1-benzylidene-1H-indene which is substituted at positions 2, 3, and 5 by methyl, carboxymethyl, and fluorine respectively, and in which the phenyl group of the benzylidene moiety is substituted at the para position by a methylsulfinyl group. It is a prodrug for the corresponding sulfide, a non-steroidal anti-inflammatory drug, used particularly in the treatment of acute and chronic inflammatory conditions. It has a role as a non-steroidal anti-inflammatory drug, an analgesic, a non-narcotic analgesic, an antipyretic, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor, an antineoplastic agent, a prodrug, a tocolytic agent and an apoptosis inducer. It is a sulfoxide, a monocarboxylic acid and an organofluorine compound. It is functionally related to an acetic acid.
Source: ChEBI
| Molecular formula | C20H17FO3S |
|---|---|
| Molecular weight | 356.4 g/mol |
| IUPAC name | 2-[(3Z)-6-fluoro-2-methyl-3-[(4-methylsulfinylphenyl)methylidene]inden-1-yl]acetic acid |
| InChIKey | MLKXDPUZXIRXEP-MFOYZWKCSA-N |
| SMILES | CC\1=C(C2=C(/C1=C\C3=CC=C(C=C3)S(=O)C)C=CC(=C2)F)CC(=O)O |
Computed by PubChem (NCBI)
Synonyms:
sulindac, Clinoril, Arthrocine, Artribid, Sulindaco, Sulindacum, Citireuma, Sulindac sulfoxide, Aflodac, Imbaral