Products 500-92-5

CAS 500-92-5 appears in our catalog under these names: Proguanil, 95%, Chlorguanide (Proguanil), Proguanil, Proguanil 98%, Proguanil, 98%, 98%. Offered by: Combi-blocks, Chemat Brand, TargetMol, GLPBio, Biosynth. Available pack sizes: 1g, 5g, 250mg, on request, 5mg, 10mg, 10mM (in 1ml dmso), 25mg.

Structural formula: {0} (CAS {1})

Proguanil is a biguanide compound which has isopropyl and p-chlorophenyl substituents on the terminal N atoms. A prophylactic antimalarial drug, it works by inhibiting the enzyme dihydrofolate reductase, which is involved in the reproduction of the malaria parasites Plasmodium falciparum and P. vivax within the red blood cells. It has a role as an antiprotozoal drug, an antimalarial and an EC 1.5.1.3 (dihydrofolate reductase) inhibitor. It is a member of biguanides and a member of monochlorobenzenes.

Source: ChEBI

Identity
Molecular formulaC11H16ClN5
Molecular weight253.73 g/mol
IUPAC name(1E)-1-[amino-(4-chloroanilino)methylidene]-2-propan-2-ylguanidine
InChIKeySSOLNOMRVKKSON-UHFFFAOYSA-N
SMILESCC(C)N=C(N)/N=C(\N)/NC1=CC=C(C=C1)Cl

Computed by PubChem (NCBI)