CAS 500-92-5 appears in our catalog under these names: Proguanil, 95%, Chlorguanide (Proguanil), Proguanil, Proguanil 98%, Proguanil, 98%, 98%. Offered by: Combi-blocks, Chemat Brand, TargetMol, GLPBio, Biosynth. Available pack sizes: 1g, 5g, 250mg, on request, 5mg, 10mg, 10mM (in 1ml dmso), 25mg.
Proguanil is a biguanide compound which has isopropyl and p-chlorophenyl substituents on the terminal N atoms. A prophylactic antimalarial drug, it works by inhibiting the enzyme dihydrofolate reductase, which is involved in the reproduction of the malaria parasites Plasmodium falciparum and P. vivax within the red blood cells. It has a role as an antiprotozoal drug, an antimalarial and an EC 1.5.1.3 (dihydrofolate reductase) inhibitor. It is a member of biguanides and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C11H16ClN5 |
|---|---|
| Molecular weight | 253.73 g/mol |
| IUPAC name | (1E)-1-[amino-(4-chloroanilino)methylidene]-2-propan-2-ylguanidine |
| InChIKey | SSOLNOMRVKKSON-UHFFFAOYSA-N |
| SMILES | CC(C)N=C(N)/N=C(\N)/NC1=CC=C(C=C1)Cl |
Computed by PubChem (NCBI)