Products 58-54-8
CAS 58-54-8 appears in our catalog under these names: Ethacrynic acid, 95%, Ethacrynic Acid, Ethacrynic Acid, >95% (HPLC), Etacrynic Acid, Ethacrynic acid/ 99.15% (existing batch purity). Offered by: Combi-blocks, Chemat Brand, TRC, Mikromol, LoGiCal. Available pack sizes: 1g, 5g, 250mg, on request, 100mg, 10mg, 25mg, 50mg.
Etacrynic acid is an aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor. It has a role as an ion transport inhibitor, an EC 2.5.1.18 (glutathione transferase) inhibitor and a loop diuretic. It is a dichlorobenzene, a monocarboxylic acid, an aromatic ether and an aromatic ketone. It is functionally related to an acetic acid.
Source: ChEBI
| Molecular formula | C13H12Cl2O4 |
|---|---|
| Molecular weight | 303.13 g/mol |
| IUPAC name | 2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid |
| InChIKey | AVOLMBLBETYQHX-UHFFFAOYSA-N |
| SMILES | CCC(=C)C(=O)C1=C(C(=C(C=C1)OCC(=O)O)Cl)Cl |
Computed by PubChem (NCBI)
Synonyms:
ETHACRYNIC ACID, Etacrynic Acid, Etacrinic acid, Hydromedin, Taladren, Hidromedin, Crinuryl, Edecril, Edecrina, Endecril