Products 71294-60-5
CAS 71294-60-5 is the registry number for Rohitukine. Offered by: MedChemExpress. Available pack sizes: Get quote.
Rohitukine is a member of the class of chromones that is 4H-chromen-4-one in which the hydrogens at positions 2,5,7 and 8 are replaced by methyl, hydroxy, hydroxy, and (3S,4R)-3-hydroxy-1-methylpiperidin-4-yl groups, respectively. It is an alkaloid initially isolated from Amoora rohituka and is a precursor of the anti-cancer compound flavopiridol. It has a role as an antineoplastic agent, an anticholesteremic drug, an anti-ulcer drug, an anti-inflammatory agent, an antileishmanial agent, a plant metabolite, a fungal metabolite and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is an alkaloid, a member of chromones, a member of resorcinols, a hydroxypiperidine and a tertiary amino compound.
Source: ChEBI
| Molecular formula | C16H19NO5 |
|---|---|
| Molecular weight | 305.32 g/mol |
| IUPAC name | 5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-2-methylchromen-4-one |
| InChIKey | MOCVYVBNJQIVOV-TVQRCGJNSA-N |
| SMILES | CC1=CC(=O)C2=C(O1)C(=C(C=C2O)O)[C@H]3CCN(C[C@H]3O)C |
Computed by PubChem (NCBI)
Synonyms:
Rohitukine, 5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-2-methylchromen-4-one, 5,7-dihydroxy-8-((3S,4R)-3-hydroxy-1-methylpiperidin-4-yl)-2-methylchromen-4-one, 5,7-Dihydroxy-8-[(3R,4S)-3-hydroxy-1-methylpiperidin-4-yl]-2-methylchromen-4-one, orb1699459, MOCVYVBNJQIVOV-TVQRCGJNSA-N, 5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidyl]-2-methyl-chromen-4-one