CAS 778546-51-3 appears in our catalog under these names: (1R,3S)-3-(Adamantan-1-yl)-1-(aminomethyl)isochromane-5,6-diol, 98%, A-77636. Offered by: Chemat Brand, MedChemExpress. Available pack sizes: on request, Get quote.
(1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol is an isochromene that is 3,4-dihydroisochromene-5,6-diol bearing additional aminomethyl and 1-adamantyl substituents at positions 1 and 3 respectively (the 1R,3S-diastereomer). Potent and selective dopamine D1-like receptor agonist (pEC50 values are 8.97 and < 5 for D1-like and D2-like receptors respectively). Displays anti-Parkinsonian activity following oral administration in vivo. It has a role as an antiparkinson drug and a dopamine agonist. It is a member of catechols, a member of isochromenes, a primary amino compound and a member of adamantanes. It is a conjugate base of a (1R,3S)-3-(adamantan-1-yl)-1-(ammoniomethyl)-3,4-dihydroisochromene-5,6-diol(1+).
Source: ChEBI
| Molecular formula | C20H27NO3 |
|---|---|
| Molecular weight | 329.4 g/mol |
| IUPAC name | (1R,3S)-3-(1-adamantyl)-1-(aminomethyl)-3,4-dihydro-1H-isochromene-5,6-diol |
| InChIKey | QLJOSZATCBCBDR-DFKUFRTHSA-N |
| SMILES | C1[C@H](O[C@H](C2=C1C(=C(C=C2)O)O)CN)C34CC5CC(C3)CC(C5)C4 |
Computed by PubChem (NCBI)