CAS 82159-09-9 appears in our catalog under these names: Epalrestat, Epalrestat, >95% (HPLC), Epalrestat/ 99.54% (existing batch purity), Epalrestat, >98.0%(HPLC)(T), Epalrestat 95%. Offered by: Chemat Brand, TRC, TargetMol, GLPBio, TCI. Available pack sizes: on request, 100mg, 1g, 50mg, 10mg, 25mg, 200mg, 500mg.
Epalrestat is a monocarboxylic acid that is 1,3-thiazolidine which is substituted on the nitrogen by a carboxymethyl group, at positions 2 and 4 by thioxo and oxo groups, respectively, and at position 5 by a 2-methyl-3-phenylprop-2-en-1-ylidene group. It is an inhibitor of aldose reductase (which catalyses the conversion of glucose to sorbitol) and is used for the treatment of some diabetic complications, including neuropathy. It has a role as an EC 1.1.1.21 (aldehyde reductase) inhibitor. It is a monocarboxylic acid and a member of thiazolidines.
Source: ChEBI
| Molecular formula | C15H13NO3S2 |
|---|---|
| Molecular weight | 319.4 g/mol |
| IUPAC name | 2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid |
| InChIKey | CHNUOJQWGUIOLD-NFZZJPOKSA-N |
| SMILES | C/C(=C\C1=CC=CC=C1)/C=C\2/C(=O)N(C(=S)S2)CC(=O)O |
Computed by PubChem (NCBI)