rel-4-(4-((4-((1R,2S)-2-Aminocyclopropyl)phenyl)amino)-4-oxobutyl)-N-(2-aminophenyl)benzamide

cas: 1808113-09-8 — see every product listed under this CAS number, including other names

rel-4-(4-((4-((1R,2S)-2-Aminocyclopropyl)phenyl)amino)-4-oxobutyl)-N-(2-aminophenyl)benzamide (CAS 1808113-09-8) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 200mg. Offered by: Chemat.

• 2D
• 3D

Corin is a dual inhibitor of histone lysine specific demethylase (LSD1) and histone deacetylase (HDAC), with a Ki(inact) of 110 nM for LSD1 and an IC50 of 147 nM for HDAC1.

Source: ChEBI

Identity

Molecular formula	C26H28N4O2
Molecular weight	428.5 g/mol
IUPAC name	4-[4-[4-[(1S,2R)-2-aminocyclopropyl]anilino]-4-oxobutyl]-N-(2-aminophenyl)benzamide
InChIKey	TYTLARZOLKJSJU-JTHBVZDNSA-N
SMILES	C1[C@H]([C@@H]1N)C2=CC=C(C=C2)NC(=O)CCCC3=CC=C(C=C3)C(=O)NC4=CC=CC=C4N

Computed by PubChem (NCBI)

Synonyms: CORIN, Corin?, orb1710004

Isomers (same molecular formula)

N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]naphthalene-2-carboxamide C₂₆H₂₈N₄O₂

N-[(3E)-3-benzylidene-9-oxo-1,2-dihydropyrrolo[2,1-b]quinazolin-6-yl]-3-piperidin-1-ylpropanamide C₂₆H₂₈N₄O₂

4-amino-N-[2-(4-benzoylpiperidin-1-yl)ethyl]-N-pyridin-3-ylbenzamide C₂₆H₂₈N₄O₂

2-amino-3',6'-bis(ethylamino)-2',7'-dimethylspiro[isoindole-3,9'-xanthene]-1-one C₂₆H₂₈N₄O₂

(2S)-2-azido-6-[[(4-methylphenyl)-diphenylmethyl]amino]hexanoic acid C₂₆H₂₈N₄O₂

N-[(S)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methyl]pyridine-2-carboxamide C₂₆H₂₈N₄O₂

7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide C₂₆H₂₈N₄O₂

1-[(E)-3-[3-(3,4-dimethylphenyl)-1-phenylpyrazol-4-yl]prop-2-enoyl]piperidine-2-carboxamide C₂₆H₂₈N₄O₂

3-[1-[(4-methyl-6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl)methyl]piperidin-4-yl]-1H-benzimidazol-2-one C₂₆H₂₈N₄O₂