(αR,βR)-α-(2,4-Difluorophenyl)-β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidineethanol, 98%, 98%

cas: 164650-44-6 — see every product listed under this CAS number, including other names

(αR,βR)-α-(2,4-Difluorophenyl)-β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidineethanol, 98%, 98% (CAS 164650-44-6) is a chemical reagent available from Chemat. Available pack sizes: 25mg, 100mg, 250mg, 1g, 5g, 5mg, 10mg, 10g. Offered by: Chemat.

brandChemat
catalog numberCh112V1H-25mg
cas164650-44-6
size25mg
availability 13.25g
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Available pack sizes

brand size price
Chemat 25mg 174.80 Pln
Chemat 100mg 198.80 Pln
Chemat 250mg 266.00 Pln
Chemat 1g 582.80 Pln
Chemat 5g 1634.00 Pln
Chemat 5mg 102.80 Pln
Chemat 10mg 122.00 Pln
Chemat 10g 3165.20 Pln

properties

purity98%
delivery time3 weeks
Structural formula: {0} (CAS {1})

Efinaconazole is a member of the class of triazoles that is butan-2-ol which is substituted at positions 1, 2, and 3 by 1,2,4-triazol-1-yl, 2,4-difluorophenyl, and 4-methylenepiperidin-1-yl groups, respectively (the 2R,3R stereoisomer). It is an antifungal drug used for the topical treatment of onychomycosis (a nail infection caused mainly by dermatophytes). It has a role as an EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor. It is a member of piperidines, a tertiary alcohol, an organofluorine compound, a tertiary amino compound, an olefinic compound, a conazole antifungal drug and a triazole antifungal drug.

Source: ChEBI

Identity
Molecular formulaC18H22F2N4O
Molecular weight348.4 g/mol
IUPAC name(2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol
InChIKeyNFEZZTICAUWDHU-RDTXWAMCSA-N
SMILESC[C@H]([C@](CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3CCC(=C)CC3

Computed by PubChem (NCBI)

Synonyms: EFINACONAZOLE, JUBLIA, efinaconazol, Clenafin, Kp 103, efinaconazolum, Efinaconazole [INN], Efinaconazole [USAN:INN], Clenafin (TN), Jublia (TN)
Related forms of this compound
(2R,3S)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol C18H22F2N4O
(2S,3R)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol C18H22F2N4O
(2S,3S)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol C18H22F2N4O
(2R,3R)-2-(2,4-difluorophenyl)-3-(2,2,6,6-tetradeuterio-4-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol C18H22F2N4O
Isomers (same molecular formula)
(2R,3R)-6-fluoro-2-methyl-4'-methylidene-3-(1,2,4-triazol-1-ylmethyl)spiro[2H-indol-1-ium-1,1'-azinan-1-ium]-3-ol fluoride C18H22F2N4O
(2R,3R)-2-(2,4-difluorophenyl)-3-(4-methyl-3,6-dihydro-2H-pyridin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol C18H22F2N4O
(2R,3R)-2-(2,4-difluorophenyl)-3-(3-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol C18H22F2N4O
1-(4-fluorophenyl)-4-[4-(5-fluoropyrimidin-2-yl)piperazin-1-yl]butan-1-ol C18H22F2N4O
N-(1-tert-butyl-6-cyano-4,7-difluorobenzimidazol-2-yl)-3,3-dimethylbutanamide C18H22F2N4O

Also listed as

Efinaconazole Chemat Brand CAS 164650-44-6
Efinaconazole, >95% (HPLC) TRC CAS 164650-44-6
Efinaconazole/ 99.7% (existing batch purity) TargetMol CAS 164650-44-6
Efinaconazole, 98+% Thermo Scientific (Acros) CAS 164650-44-6
Efinaconazole, 99.84% MedChemExpress CAS 164650-44-6
Efinaconazole, 250 mg Roth CAS 164650-44-6
Efinaconazole, 500 mg Roth CAS 164650-44-6
Efinaconazole, 1 g Roth CAS 164650-44-6
Efinaconazole, 2 g Roth CAS 164650-44-6
(2R,3R)-2-(2,4-DIFLUOROPHENYL)-3-(4-METHYLENEPIPERIDIN-1-YL)-1-(1H-1,2,4-TRIAZOL-1-YL)BUTAN-2-OL, 97% Fluorochem CAS 164650-44-6