Efinaconazole, >95% (HPLC)

cas: 164650-44-6 — see every product listed under this CAS number, including other names

Efinaconazole, >95% (HPLC) (CAS 164650-44-6) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 1mg, 50mg. Offered by: TRC.

brandTRC
catalog numberTRC-E435070-100MG
cas164650-44-6
size100mg
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Available pack sizes

brand size price
TRC 100mg price on request
TRC 1mg price on request
TRC 50mg price on request

properties

purity>95% (HPLC)
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Efinaconazole is a member of the class of triazoles that is butan-2-ol which is substituted at positions 1, 2, and 3 by 1,2,4-triazol-1-yl, 2,4-difluorophenyl, and 4-methylenepiperidin-1-yl groups, respectively (the 2R,3R stereoisomer). It is an antifungal drug used for the topical treatment of onychomycosis (a nail infection caused mainly by dermatophytes). It has a role as an EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor. It is a member of piperidines, a tertiary alcohol, an organofluorine compound, a tertiary amino compound, an olefinic compound, a conazole antifungal drug and a triazole antifungal drug.

Source: ChEBI

Identity
Molecular formulaC18H22F2N4O
Molecular weight348.4 g/mol
IUPAC name(2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol
InChIKeyNFEZZTICAUWDHU-RDTXWAMCSA-N
SMILESC[C@H]([C@](CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3CCC(=C)CC3

Computed by PubChem (NCBI)

Synonyms: EFINACONAZOLE, JUBLIA, efinaconazol, Clenafin, Kp 103, efinaconazolum, Efinaconazole [INN], Efinaconazole [USAN:INN], Clenafin (TN), Jublia (TN)
Related forms of this compound
(2R,3S)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol C18H22F2N4O
(2S,3R)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol C18H22F2N4O
(2S,3S)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol C18H22F2N4O
(2R,3R)-2-(2,4-difluorophenyl)-3-(2,2,6,6-tetradeuterio-4-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol C18H22F2N4O
Isomers (same molecular formula)
(2R,3R)-6-fluoro-2-methyl-4'-methylidene-3-(1,2,4-triazol-1-ylmethyl)spiro[2H-indol-1-ium-1,1'-azinan-1-ium]-3-ol fluoride C18H22F2N4O
(2R,3R)-2-(2,4-difluorophenyl)-3-(4-methyl-3,6-dihydro-2H-pyridin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol C18H22F2N4O
(2R,3R)-2-(2,4-difluorophenyl)-3-(3-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol C18H22F2N4O
1-(4-fluorophenyl)-4-[4-(5-fluoropyrimidin-2-yl)piperazin-1-yl]butan-1-ol C18H22F2N4O
N-(1-tert-butyl-6-cyano-4,7-difluorobenzimidazol-2-yl)-3,3-dimethylbutanamide C18H22F2N4O

Also listed as

Efinaconazole Chemat Brand CAS 164650-44-6
Efinaconazole/ 99.7% (existing batch purity) TargetMol CAS 164650-44-6
Efinaconazole, 98+% Thermo Scientific (Acros) CAS 164650-44-6
(αR,βR)-α-(2,4-Difluorophenyl)-β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidineethanol, 98%, 98% Chemat CAS 164650-44-6
Efinaconazole, 99.84% MedChemExpress CAS 164650-44-6
Efinaconazole, 250 mg Roth CAS 164650-44-6
Efinaconazole, 500 mg Roth CAS 164650-44-6
Efinaconazole, 1 g Roth CAS 164650-44-6
Efinaconazole, 2 g Roth CAS 164650-44-6
(2R,3R)-2-(2,4-DIFLUOROPHENYL)-3-(4-METHYLENEPIPERIDIN-1-YL)-1-(1H-1,2,4-TRIAZOL-1-YL)BUTAN-2-OL, 97% Fluorochem CAS 164650-44-6