Efinaconazole

cas: 164650-44-6 — see every product listed under this CAS number, including other names

Efinaconazole (CAS 164650-44-6) is a chemical reagent available from Chemat. Available pack sizes: on request, 25mg, 10mg, 100mg, 5mg, 10mM (in 1ml dmso), 50mg, 500mg. Offered by: Chemat Brand, Dr. Ehrenstorfer, GLPBio, Biosynth.

brandChemat Brand
catalog numberAO-E0053.17
cas164650-44-6
sizeon request
availability In stock
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Available pack sizes

brand size price
Chemat Brand on request price on request
Chemat Brand on request price on request
Dr. Ehrenstorfer 25mg price on request
GLPBio 10mg 760.86 Pln
GLPBio 100mg 1757.80 Pln
GLPBio 5mg 657.89 Pln
GLPBio 10mM (in 1ml dmso) 1720.36 Pln
GLPBio 50mg 1369.32 Pln
Biosynth 500mg price on request
Biosynth 250mg price on request
Biosynth 1000mg price on request
Biosynth 2000mg price on request
Biosynth 5000mg price on request

properties

delivery timeTo be confirmed by Chemat
purityNo data
Structural formula: {0} (CAS {1})

Efinaconazole is a member of the class of triazoles that is butan-2-ol which is substituted at positions 1, 2, and 3 by 1,2,4-triazol-1-yl, 2,4-difluorophenyl, and 4-methylenepiperidin-1-yl groups, respectively (the 2R,3R stereoisomer). It is an antifungal drug used for the topical treatment of onychomycosis (a nail infection caused mainly by dermatophytes). It has a role as an EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor. It is a member of piperidines, a tertiary alcohol, an organofluorine compound, a tertiary amino compound, an olefinic compound, a conazole antifungal drug and a triazole antifungal drug.

Source: ChEBI

Identity
Molecular formulaC18H22F2N4O
Molecular weight348.4 g/mol
IUPAC name(2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol
InChIKeyNFEZZTICAUWDHU-RDTXWAMCSA-N
SMILESC[C@H]([C@](CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3CCC(=C)CC3

Computed by PubChem (NCBI)

Synonyms: EFINACONAZOLE, JUBLIA, efinaconazol, Clenafin, Kp 103, efinaconazolum, Efinaconazole [INN], Efinaconazole [USAN:INN], Clenafin (TN), Jublia (TN)
Related forms of this compound
(2R,3S)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol C18H22F2N4O
(2S,3R)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol C18H22F2N4O
(2S,3S)-2-(2,4-difluorophenyl)-3-(4-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol C18H22F2N4O
Isomers (same molecular formula)
(2R,3R)-6-fluoro-2-methyl-4'-methylidene-3-(1,2,4-triazol-1-ylmethyl)spiro[2H-indol-1-ium-1,1'-azinan-1-ium]-3-ol fluoride C18H22F2N4O
(2R,3R)-2-(2,4-difluorophenyl)-3-(4-methyl-3,6-dihydro-2H-pyridin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol C18H22F2N4O
(2R,3R)-2-(2,4-difluorophenyl)-3-(3-methylidenepiperidin-1-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol C18H22F2N4O

Also listed as

Efinaconazole, >95% (HPLC) TRC CAS 164650-44-6
Efinaconazole/ 99.7% (existing batch purity) TargetMol CAS 164650-44-6
Efinaconazole, 98+% Thermo Scientific (Acros) CAS 164650-44-6
(αR,βR)-α-(2,4-Difluorophenyl)-β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidineethanol, 98%, 98% Chemat CAS 164650-44-6
Efinaconazole, 99.84% MedChemExpress CAS 164650-44-6
Efinaconazole, 250 mg Roth CAS 164650-44-6
Efinaconazole, 500 mg Roth CAS 164650-44-6
Efinaconazole, 1 g Roth CAS 164650-44-6
Efinaconazole, 2 g Roth CAS 164650-44-6
(2R,3R)-2-(2,4-DIFLUOROPHENYL)-3-(4-METHYLENEPIPERIDIN-1-YL)-1-(1H-1,2,4-TRIAZOL-1-YL)BUTAN-2-OL, 97% Fluorochem CAS 164650-44-6